You can apply Serrini Nano IN 1 Gel on the affected area 2 to 4 times daily depending on the severity Gently and evenly rub the gel into the skin Avoid excessive use and do not cover the treated area with a bandage or plaster This medication is generally safe with minimal side effects However you may experience skin rash itching redness or a burning sensation In rare cases a severe allergic reaction may occur characterized by a rash with blisters If you develop such symptoms promptly inform your doctor Serrini Nano IN 1 Gel is contraindicated during pregnancy and breastfeeding Additionally if you are already taking diclofenac or similar tablets avoid using this gel