To avoid an upset stomach it is recommended to take Prednosis 16mg Tablet with food Swallow the tablet whole with water and take it at the same times each day Your doctor will determine the appropriate dose and frequency of taking this medication which may be adjusted depending on its effectiveness Even if you feel well it is important to take this medicine regularly to obtain maximum benefits The most common side effects of Prednosis 16mg Tablet include a decrease in bone density weight gain mood changes upset stomach and behavioral changes If these side effects bother you or persist it is advisable to consult your doctor Taking this medication may also weaken your ability to fight infections If you experience any signs of infection such as fever or sore throat inform your doctor It is crucial to inform your doctor about any existing medical conditions particularly poor blood circulation diabetes and immune system disorders Additionally disclose all other medications you are currently taking especially steroids