prasurel (PRASUGREL)
Introduction to Prasurel
Prasurel is a medication primarily used to prevent blood clots in patients with acute coronary syndrome. It is especially beneficial for those undergoing procedures like stent... See More
What is Prasurel?
Prasurel helps reduce the risk of heart or blood vessel problems like heart attacks, strokes, and blood clots in stents. It works by preventing platelets from clumping together and forming clots.
What is the usual dose of Prasurel?
This medication is taken by mouth. The first dose is 60 mg, and then you take 10 mg once a day after that. There is no information about how much children should take.
How do I take Prasurel?
Prasurel can be taken with or without food. There are no specific food restrictions while taking this medication. However, it is important to swallow the tablet whole, without crushing or chewing it. If you have difficulty swallowing pills, consult your doctor for alternative options. Always take the medication as prescribed and follow the doctor's instructions.
For how long do I take Prasurel?
The typical duration of Prasurel treatment is generally 6 to 12 months for patients with acute coronary syndromes undergoing percutaneous coronary intervention. Some studies indicate that treatment may extend up to 14.5 months or longer, depending on individual patient circumstances. It's essential for patients to consult their healthcare provider to determine the appropriate duration based on their specific health needs and risks.
What is Prasurel used for?
Prasurel is primarily indicated for the prevention of blood clots in patients with acute coronary syndrome (ACS), specifically those undergoing percutaneous coronary intervention (PCI), including stent placement. It is used in combination with aspirin to reduce the risk of thrombotic events like heart attacks, strokes, and other cardiovascular complications in these patients.
How long does it take for Prasurel to start working?
Prasurel typically starts working within 30 minutes to 1 hour after ingestion, with its full effects usually seen within a few hours. This rapid onset helps in reducing the risk of blood clot formation, particularly in patients undergoing procedures like angioplasty or those with acute coronary syndrome. However, its maximum effect may take a few days of regular use.
Is Prasurel effective?
Prasurel has been proven effective through clinical studies, particularly in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). The TRITON-TIMI 38 trial showed that Prasurel significantly reduced the risk of cardiovascular events (like heart attacks, stent thrombosis, and death from cardiovascular causes) compared to clopidogrel. Its faster and more potent platelet inhibition contributed to these outcomes, particularly in high-risk patients.
How does one know if Prasurel is working?
The benefit of Prasurel is primarily evaluated through clinical trials and patient outcomes. Key metrics include the reduction in the risk of major cardiovascular events such as heart attack, stroke, and death from cardiovascular causes, particularly in patients with acute coronary syndrome (ACS). Additionally, platelet inhibition is monitored to assess the drug's effectiveness in preventing thrombus formation, often measured by platelet function tests. Regular follow-up visits help track patient progress and any side effects.
How does Prasurel work?
Prasurel is an antiplatelet medication that works by inhibiting platelet aggregation. It irreversibly blocks the P2Y12 receptor on platelets, preventing adenosine diphosphate (ADP) from activating platelets. This inhibition reduces platelet activation and aggregation, thereby preventing the formation of blood clots. By reducing clot formation, Prasurel helps to lower the risk of heart attacks, strokes, and other thrombotic events in patients with acute coronary syndrome.
Who should avoid taking Prasurel?
Prasurel is contraindicated in individuals with active bleeding disorders, a history of intracranial hemorrhage, or severe hepatic impairment. It should be used with caution in people with a history of gastrointestinal bleeding, stroke, or those undergoing surgery. Warnings include an increased risk of bleeding, including fatal bleeding, and the need for careful monitoring during treatment, particularly in elderly patients and those with low body weight.
Can I take Prasurel with vitamins or supplements?
Prasurel can interact with certain vitamins and supplements, particularly those that affect blood clotting. Vitamin E, fish oil, and other omega-3 fatty acids, which have blood-thinning effects, may increase the risk of bleeding when used with Prasurel. It's important to inform a healthcare provider about any supplements being taken to adjust treatment appropriately and minimize risks.
Can I take Prasurel with other prescription drugs?
Prasurel can interact with medications that increase bleeding risk, including anticoagulants (warfarin, heparin), antiplatelet drugs (aspirin, clopidogrel), and NSAIDs, which may heighten bleeding risks. Proton pump inhibitors (e.g., omeprazole) may reduce Prasurel’s effectiveness. Always consult a healthcare provider before using Prasurel with other drugs to avoid harmful interactions.
Can Prasurel be taken safely while pregnant?
Prasurel is classified as Pregnancy Category B by the FDA, meaning that it is not expected to harm an unborn baby based on animal studies. However, there are no well-controlled studies in pregnant women, so it should be used only if clearly needed. It is recommended to consult a healthcare provider before using Prasurel during pregnancy.
Can Prasurel be taken safely while breastfeeding?
Prasurel is not recommended for use during breastfeeding, as it is not known whether it passes into breast milk. Given the potential for serious side effects, such as bleeding, it is advised to consult a healthcare provider before using Prasurel while breastfeeding. Alternative treatments may be considered to avoid potential risks to the infant.
Is Prasurel safe for the elderly?
Prasurel is a medication used to prevent blood clots. It's usually not given to people who are 75 or older because it can make them more likely to bleed, sometimes seriously or even fatally. This is more common with Prasurel than with a similar medication called clopidogrel. However, people who are 75 or older may still be given Prasurel if they have certain conditions, like diabetes or a previous heart attack. In these cases, the benefits of the medication may outweigh the risks. It's important to note that the risk of bleeding increases with age, but the risk of bleeding with Prasurel compared to clopidogrel is about the same for people of all ages.
How should I store Prasurel?
Store the Prasurel at normal room temperature, between 59°F to 86°F (15°C to 30°C). Keep the Prasurel in their original container, with the lid tightly closed. The container includes a drying agent to absorb moisture, so don't remove it.
Does Prasurel make people tired or drowsy?
Prasurel doesn’t usually cause tiredness or drowsiness. If you feel unusually tired, talk to your doctor.
Does Prasurel cause stomach upset?
Some people may experience nausea or stomach discomfort. Taking it with food might help. Contact your doctor if it continues.
Does Prasurel affect sleep?
It typically doesn’t affect sleep. Let your doctor know if you have trouble sleeping.
Does Prasurel make it hard to think or concentrate?
This medicine usually doesn’t affect your thinking. If you notice confusion or trouble focusing, consult your doctor.
Does Prasurel affect mood?
Mood changes are uncommon. If you feel unusually emotional or notice mood swings, inform your doctor.
Does Prasurel interfere with sexual function?
There’s no evidence suggesting Prasurel impacts sexual function.
Does Prasurel affect appetite?
Prasurel rarely affects appetite. Let your doctor know if you notice any significant changes in your eating habits.
Does Prasurel cause weight gain?
This medicine is not known to cause weight gain.
Does Prasurel cause headaches?
Headaches can sometimes happen. If they persist or bother you, talk to your doctor.
Does Prasurel limit driving?
Prasurel doesn’t directly affect driving. However, avoid driving if you feel dizzy or unwell.
Is it safe to drink alcohol while taking Prasurel?
Alcohol increases the risk of bleeding or stomach problems, so it’s best to avoid it with this medicine.
Is it safe to drink coffee or tea while taking Prasurel?
You can drink coffee or tea, but don’t overdo it if you notice stomach upset.
Is it safe to exercise while taking Prasurel?
Exercise is fine, but avoid high-risk activities since this medicine increases bleeding risks. Follow your doctor’s guidance.
What are Prasurel possible harms and risks?
The most common side effects of Prasurel include bleeding, bruising, and nosebleeds. Other less frequent side effects may include dizziness, headache, rash, or gastrointestinal symptoms such as nausea. Significant adverse effects include serious bleeding events (such as intracranial hemorrhage or gastrointestinal bleeding), severe allergic reactions, and thrombocytopenia (low platelet count). These can increase the risk of major bleeding and require immediate medical attention.
Available in 2 variations
Prasurel 10mg Tablet
Prasurel 10mg Tablet
Prasugrel (10mg)
strip of 10 tablets
Prasurel 5mg Tablet
Prasurel 5mg Tablet
Prasugrel (5mg)
strip of 10 tablets
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