palica (PALIPERIDONE)
What is Palica?
Palica is an antipsychotic medication used to treat schizophrenia and schizoaffective disorder. It helps restore the balance of certain neurotransmitters in the brain, improving mood, thinking, and behavior. It is available in extended-release tablet form and as an injectable. This medication reduces symptoms like hallucinations, delusions, and mood swings, helping patients lead a more stable life.
What is the usual dose of Palica?
For schizophrenia, adults typically take 3 to 12 mg of Palica daily, starting with 6 mg once a day. For schizoaffective disorder, doses range from 6 to 12 mg daily. Dosage is adjusted based on response and tolerance. The extended-release tablets should be swallowed whole, not chewed or crushed. Injectable doses vary depending on the formulation.
How do I take Palica?
Palica extended-release tablets should be taken once daily, in the morning, with or without food. They must be swallowed whole with water and should not be split or chewed. The injectable form is given by a healthcare professional. Avoid alcohol while taking this medication, as it can increase drowsiness and dizziness.
For how long do I take Palica?
Treatment duration varies based on the condition. Schizophrenia and schizoaffective disorder often require long-term treatment to prevent relapse. Your doctor will determine the appropriate length of therapy. Do not stop taking Palica suddenly, as it may cause withdrawal symptoms or worsen your condition.
What is Palica used for?
Palica is primarily used to treat schizophrenia and schizoaffective disorder. It helps manage symptoms such as hallucinations, delusions, mood instability, and disorganized thinking. By stabilizing dopamine and serotonin levels in the brain, it improves mental function and overall quality of life for people with these conditions.
How long does it take for Palica to start working?
Palica may start working within a few days, but full effects can take several weeks. Some symptoms like agitation or hallucinations may improve within 1 to 2 weeks, while others, such as disorganized thinking, may take longer. It is important to continue taking the medication as prescribed, even if symptoms improve.
Is Palica effective?
Yes, studies show Palica is effective in reducing schizophrenia and schizoaffective disorder symptoms. It helps prevent relapses and improves patients’ ability to function in daily life. The extended-release and injectable formulations provide consistent symptom control with fewer fluctuations in blood levels compared to older antipsychotic drugs.
How does one know if Palica is working?
Improvement in symptoms such as reduced hallucinations, clearer thinking, and better emotional stability are signs that Palica is working. It may take several weeks for full benefits. Regular follow-ups with a doctor will help monitor progress and adjust dosage if needed.
How does Palica work?
Palica blocks dopamine (D2) and serotonin (5-HT2A) receptors in the brain, reducing psychotic symptoms and mood instability. By balancing these neurotransmitters, it helps regulate emotions, thoughts, and behaviors, making it effective for schizophrenia and schizoaffective disorder.
Who should avoid taking Palica?
People with severe kidney disease, a history of severe allergic reactions to Palica or risperidone, or those with neuroleptic malignant syndrome (NMS) should avoid this medication. It should be used with caution in people with heart disease, seizures, or a history of low white blood cell counts.
Can I take Palica with vitamins or supplements?
Palica can interact with some supplements, especially St. John’s Wort, which may reduce its effectiveness. Calcium and magnesium supplements should be taken separately, as they can affect absorption. Always inform your doctor about any supplements you are taking before starting Palica.
Can I take Palica with other prescription drugs?
Palica may interact with antihypertensive drugs, sedatives, antidepressants, and other antipsychotics, increasing the risk of side effects like drowsiness or low blood pressure. Avoid combining it with dopamine agonists like levodopa, as it may reduce their effectiveness. Always consult your doctor before adding new medications.
Can Palica be taken safely while pregnant?
Palica should only be used during pregnancy if the benefits outweigh the risks. In the third trimester, it may cause withdrawal symptoms in newborns, such as breathing difficulties and muscle stiffness. Pregnant women should consult their doctor for a thorough risk-benefit analysis before taking Palica.
Can Palica be taken safely while breastfeeding?
Palica passes into breast milk and may cause side effects in infants, such as drowsiness or feeding difficulties. Breastfeeding while taking this medication is generally not recommended unless advised by a doctor. If necessary, formula feeding may be a safer alternative.
Is Palica safe for the elderly?
Elderly patients, especially those with dementia-related psychosis, have an increased risk of stroke and death when using antipsychotics like Palica. It should be used with caution in older adults due to increased sensitivity to side effects such as dizziness and movement disorders.
How should I store Palica?
Store Palica at room temperature (20-25°C) in a dry place, away from moisture and direct sunlight. Keep it out of reach of children. If using the injectable form, follow storage instructions provided by your healthcare provider. Do not use expired medication.
Does Palica make people tired or drowsy?
Yes, drowsiness is a common side effect of Palica, occurring in more than 10% of patients. Some people may feel fatigued or less alert, especially during the first few weeks. If drowsiness becomes severe, avoid activities that require concentration, like driving. Consult your doctor if it significantly affects your daily routine.
Does Palica cause stomach upset?
Some people may experience nausea, constipation, or stomach discomfort while taking Palica. These effects are usually mild and improve over time. Drinking plenty of fluids and eating fiber-rich foods can help. If symptoms persist or worsen, consult your doctor for possible dose adjustments or supportive treatments.
Does Palica affect sleep?
Yes, Palica can cause sleep disturbances, including insomnia or excessive sleepiness. Some patients find it harder to fall asleep, while others feel overly drowsy. If sleep problems persist, your doctor may adjust the dose or suggest taking the medication at a different time of day.
Does Palica make it hard to think or concentrate?
Some people may experience difficulty concentrating, confusion, or memory problems while taking Palica. These side effects are more common when starting the medication or after a dose increase. If cognitive issues interfere with daily life, discuss them with your doctor for possible dose adjustments.
Does Palica affect mood?
While Palica is used to stabilize mood, it may also cause mood swings, irritability, or emotional numbness in some patients. Rarely, it can lead to depression or suicidal thoughts. If you experience significant mood changes, inform your doctor immediately for proper management.
Does Palica interfere with sexual function?
Yes, Palica can affect sexual function by reducing libido, causing erectile dysfunction, or leading to delayed ejaculation. In women, it may cause changes in menstrual cycles due to increased prolactin levels. If these issues become bothersome, speak to your doctor about alternative treatments or management strategies.
Does Palica affect appetite?
Palica may increase appetite, leading to weight gain in some patients. Cravings for carbohydrates and increased hunger are common. If this leads to unhealthy weight changes, a balanced diet and regular exercise can help manage appetite.
Does Palica cause weight gain?
Yes, weight gain is a frequently reported side effect of Palica. Some patients may experience an increase in body fat due to higher appetite and metabolic changes. Regular physical activity and mindful eating habits can help prevent excessive weight gain while on this medication.
Does Palica cause headaches?
Headaches are a common side effect, affecting some people, especially when starting Palica. Staying hydrated and managing stress may help. If headaches become severe or persistent, talk to your doctor about potential adjustments or pain relief options.
Does Palica limit driving?
Palica can cause drowsiness, dizziness, and blurred vision, which may impair driving ability. If you feel overly sedated or unable to focus, avoid driving or operating machinery. Wait until you know how the medication affects you before engaging in activities requiring full alertness.
Is it safe to drink alcohol while taking Palica?
Drinking alcohol while taking Palica is not recommended. Alcohol can increase drowsiness, dizziness, and the risk of dangerous side effects like confusion or impaired motor skills. If you do drink, limit intake and monitor for adverse effects. Always consult your doctor before combining alcohol with medication.
Is it safe to drink coffee or tea while taking Palica?
Caffeinated drinks like coffee and tea are generally safe with Palica, but excessive caffeine may increase restlessness, anxiety, or heart rate changes. If you experience jitteriness or trouble sleeping, consider reducing caffeine intake. Always monitor your body’s reaction and adjust accordingly.
Is it safe to exercise while taking Palica?
Yes, regular exercise is encouraged while taking Palica to help manage weight gain and improve overall well-being. However, be cautious with strenuous activities, as this medication can cause dizziness, dehydration, or overheating. Stay hydrated, take breaks as needed, and consult your doctor if you experience unusual fatigue or weakness.
What are Palica possible harms and risks?
Common side effects include drowsiness, weight gain, dizziness, and constipation. More serious risks include high blood sugar, movement disorders (extrapyramidal symptoms), and increased prolactin levels, which may cause hormonal changes. Rarely, it can cause neuroleptic malignant syndrome (NMS), a life-threatening condition. Regular medical check-ups help manage these risks.
Available in 3 variations
Palica OD 6mg Tablet
Palica OD 6mg Tablet
Paliperidone (6mg)
strip of 10 tablets
Palica OD 3mg Tablet
Palica OD 3mg Tablet
Paliperidone (3mg)
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Palica OD 9mg Tablet
Palica OD 9mg Tablet
Paliperidone (9mg)
strip of 10 tablets
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