Please follow your doctors instructions regarding the dosage and duration of Offin 300mg Tablet You can take it with or without food but it is recommended to take it at the same time every day It is important not to miss any doses and complete the entire course of treatment even if you start feeling better Do not take a double dose to compensate for a missed dose Just take the next dose as scheduled Possible side effects of this medication include nausea and stomach pain These side effects are usually temporary and should resolve on their own However if they become bothersome or persist for a longer period please consult your doctor Diarrhea may also occur but it typically stops after completing the course of treatment If it continues or if you notice blood in your stools inform your doctor If you are allergic to any of the ingredients in this medication do not take it In rare cases some people may experience a severe allergic reaction that requires immediate medical attention Signs of a severe allergic reaction include a rash swelling of the lips tongue or face shortness of breath or breathing difficulties If you have kidney problems take special care when using this medicine