Introduction to Lupinib 400 Tablet


Lupinib 400 Tablet is a medication primarily used to treat certain types of cancer. It contains the active ingredient Imatinib mesylate, which is effective in managing conditions like chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs). This tablet is a part of a class of drugs known as tyrosine kinase inhibitors, which work by blocking the growth of cancer cells.


Composition of Lupinib 400 Tablet


The main component of Lupinib 400 Tablet is Imatinib mesylate. This ingredient is crucial in targeting specific proteins that contribute to cancer cell growth, thereby slowing down the progression of the disease.


Uses of Lupinib 400 Tablet


  • Treatment of chronic myeloid leukemia (CML)
  • Management of gastrointestinal stromal tumors (GISTs)
  • Effective in treating acute lymphoblastic leukemia (ALL)
  • Used for some rare blood and skin cancers

Side effects of Lupinib 400 Tablet


Common side effects:


  • Nausea
  • Fatigue
  • Diarrhea
  • Muscle cramps
  • Fluid retention

Serious side effects:


  • Liver toxicity
  • Heart failure
  • Severe bleeding
  • Bone marrow suppression
  • Lung complications

Precautions of Lupinib 400 Tablet


Before taking Lupinib 400 Tablet, inform your doctor if you have any pre-existing conditions such as severe liver disease, heart failure, or a history of severe allergic reactions. Pregnant women should avoid this medication due to potential harm to the fetus. Use it cautiously if you have kidney issues or severe infections.


How to Take Lupinib 400 Tablet


  • Follow your doctor's prescription carefully.
  • For CML, adults usually take 400-600 mg once daily.
  • For GISTs, the usual dose is 400 mg daily, which can be increased to 800 mg if needed.
  • For children, the dosage is based on body weight (260-340 mg/m2 daily).
  • Take the tablet with a meal and a full glass of water to reduce stomach upset.

Conclusion of Lupinib 400 Tablet


Lupinib 400 Tablet is a powerful medication used in the treatment of certain cancers. While it offers significant benefits in managing these conditions, it is essential to be aware of its side effects and take necessary precautions. Always follow your healthcare provider's instructions to ensure the best outcomes.


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Written By:

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Published At: Oct 19, 2023

Updated At: Jan 28, 2025

Reviewed By:

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Published At: Oct 19, 2023

Updated At: Jan 28, 2025

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.