losarfine (LOSARTAN)
Introduction to Losarfine
Losarfine is a medication primarily used to manage high blood pressure and other related conditions. It helps in relaxing blood vessels, making it easier for the heart to pump... See More
What is Losarfine?
Losarfine is an angiotensin II receptor blocker (ARB) commonly used to treat high blood pressure (hypertension) and heart failure. It is also prescribed to protect the kidneys in diabetic nephropathy. Losarfine works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, thus helping to relax and widen blood vessels, lowering blood pressure and improving heart function.
How do I take Losarfine?
Losarfine can be taken with or without food. There are no specific food restrictions, but avoid high-potassium foods or supplements as Losarfine can increase potassium levels. Take once daily, at the same time each day. Swallow the tablet whole, without crushing or chewing. Follow your doctor’s advice on potassium intake and other medications you may be taking.
For how long do I take Losarfine?
Losarfine is often a medicine you take for a long time, maybe even your whole life.
What is Losarfine used for?
Losarfine is indicated for treating hypertension (high blood pressure), heart failure, and diabetic nephropathy (kidney disease in diabetes). It’s also used to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy (enlarged heart). Losarfine helps lower blood pressure and protect kidney function, improving overall cardiovascular health.
How long does it take for Losarfine to start working?
Your blood pressure may go down in the first week of taking Losarfine, but it may take up to 6 weeks to feel the full effects.
Is Losarfine effective?
Evidence supporting Losarfine’s effectiveness comes from clinical trials showing it significantly reduces blood pressure, improving cardiovascular outcomes. Studies like the Losarfine Heart Failure Study demonstrated its ability to reduce symptoms and hospitalizations in heart failure patients. It also effectively protects kidney function in those with diabetic nephropathy and reduces the risk of stroke in high-risk patients.
How does one know if Losarfine is working?
The benefit of Losarfine is evaluated by regularly monitoring blood pressure to ensure it stays within the target range. In patients with heart failure or diabetic nephropathy, kidney function and creatinine levels are also monitored. Additionally, doctors may assess heart function and symptoms to determine if the medication is effectively improving overall cardiovascular health and reducing risks.
How does Losarfine work?
Losarfine works by blocking the action of angiotensin II, a hormone that constricts blood vessels and raises blood pressure. By blocking angiotensin II receptors, Losarfine helps relax and widen blood vessels, which lowers blood pressure. This action improves heart function, reduces strain on the heart, and helps protect the kidneys, particularly in people with diabetes.
Who should avoid taking Losarfine?
Losarfine is contraindicated in pregnancy, particularly in the second and third trimesters, due to risks to the fetus. It should not be used in patients with severe liver impairment or allergy to the drug. Caution is advised for those with kidney problems, low blood pressure, or high potassium levels. Regular monitoring of blood pressure, kidney function, and potassium is important.
Can I take Losarfine with vitamins or supplements?
Significant interactions with Losarfine include potassium supplements or high-potassium foods (e.g., bananas, spinach), which can increase the risk of hyperkalemia (high potassium levels). Vitamin D and calcium supplements may also affect Losarfine's effectiveness. It’s important to consult a healthcare provider before taking any vitamins or supplements to avoid interactions that could impact blood pressure or kidney function.
Can I take Losarfine with other prescription drugs?
Significant interactions with Losarfine include diuretics (e.g., spironolactone) which may increase the risk of low blood pressure or kidney problems. ACE inhibitors (e.g., enalapril) or renin inhibitors (e.g., aliskiren) can cause hyperkalemia and kidney issues. NSAIDs (e.g., ibuprofen) may reduce Losarfine’s effectiveness and harm kidney function. Always consult your doctor about all medications you're taking.
Can Losarfine be taken safely while pregnant?
Losarfine is a medication that should not be taken by pregnant women. If taken during pregnancy, it can decrease the amount of fluid surrounding the developing baby, especially in the second and third trimesters. This can cause harm to the baby's kidneys and lungs, leading to long-term health issues. If you discover you are pregnant while taking Losarfine, stop taking it and consult your doctor immediately.
Can Losarfine be taken safely while breastfeeding?
It's usually okay to breastfeed while taking Losarfine, but it's important to talk to your doctor first. However, if your baby was born prematurely, it's best to avoid taking Losarfine. Your doctor can help you decide the best course of action.
Is Losarfine safe for the elderly?
Losarfine is a medicine for high blood pressure and kidney protection in people with type 2 diabetes. In studies, a smaller percentage of older people (65 and older) took part in the high blood pressure trials compared to the diabetes trials. Doctors found Losarfine worked similarly well in both younger and older adults, but some older people might be more sensitive to it. It's important for doctors to check potassium levels in the blood regularly, and they may need to adjust the dose or stop the medicine if necessary.
How should I store Losarfine?
To keep your Losarfine medicine in good condition, store it properly. Put it in a container that closes tightly to keep out light. The temperature should stay between 59°F to 86°F (15°C to 30°C). Most importantly, keep it and all other medicines out of reach of children for safety.
Does Losarfine make people tired or drowsy?
Yes, Losarfine can cause dizziness, which was reported in 3% of patients in clinical trials. If you experience dizziness or lightheadedness, especially after getting up from a lying or sitting position, get up slowly and talk to your doctor.
Does Losarfine cause stomach upset?
Yes, Losarfine can cause stomach upset like abdominal pain, nausea, vomiting, and diarrhea. These side effects were reported in less than 2% of patients. If you experience gastrointestinal issues, consult your doctor for advice on managing these side effects.
Does Losarfine affect sleep?
Losarfine can cause sleep disorders. If you experience a change in sleep, talk to your doctor to see if they recommend any changes to your medication or sleep habits.
Does Losarfine make it hard to think or concentrate?
Yes, Losarfine may affect your ability to think or concentrate. Side effects like somnolence and headache can cause problems with concentration, attention, and memory. If you experience these side effects, talk to your doctor.
Does Losarfine affect mood?
Yes, Losarfine can affect your mood. It may cause depression. If you experience mood swings, depression, or anxiety while taking this medication, it is important to consult your doctor for further evaluation and guidance.
Does Losarfine interfere with sexual function?
Yes, Losarfine can cause impotence. If you experience sexual side effects while taking Losarfine, talk to your doctor as they may be able to adjust your dose or suggest alternative treatments.
Does Losarfine affect appetite?
There is no enough data to prove that Losarfine affects appetite.
Does Losarfine cause weight gain?
Weight gain is not a commonly reported side effect of Losarfine. In fact, it is more likely to cause weight loss in rare cases due to its potential impact on fluid retention and blood pressure.
Does Losarfine cause headaches?
Losarfine can cause headaches. If you experience headaches while taking Losarfine, talk to your doctor to see if they recommend any changes to your medication or over-the-counter pain relief.
Does Losarfine limit driving?
Losarfine can cause dizziness. If you experience dizziness, do not drive or operate machinery.
Is it safe to drink alcohol while taking Losarfine?
Alcohol can lower blood pressure, which might amplify Losarfine's effects and cause dizziness or fainting. It's best to limit alcohol intake and consult your doctor for personalized advice.
Is it safe to drink coffee or tea while taking Losarfine?
Moderate consumption of coffee or tea is generally safe, but caffeine can sometimes raise blood pressure slightly. If you're concerned, talk to your doctor or pharmacist.
Is it safe to exercise while taking Losarfine?
Regular exercise is beneficial, but since Losarfine lowers blood pressure, you may feel dizzy during activity. Speak to your doctor before starting a new or intense exercise routine to ensure safety.
What are Losarfine possible harms and risks?
Common side effects of Losarfine include dizziness, headache, fatigue, and nasal congestion. Significant adverse effects may include low blood pressure (hypotension), elevated potassium levels (hyperkalemia), and kidney problems. In rare cases, it can cause angioedema (swelling of deeper layers of skin). Serious side effects require immediate medical attention.
Available in 2 variations
Losarfine 50mg Tablet 10s
Losarfine 50mg Tablet 10s
Losartan (50mg)
strip of 10 tablets
Losarfine 25mg Tablet
Losarfine 25mg Tablet
Losartan (25mg)
strip of 10 tablets
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