duof (OFLOXACIN)
What is Duof?
Duof is an antibiotic used to treat infections like pneumonia, skin infections, and urinary tract infections. It belongs to the fluoroquinolone class and works by killing bacteria that cause infections. It inhibits bacterial enzymes necessary for DNA replication, effectively stopping bacterial growth.
What is the usual dose of Duof?
For adults, the usual dose of Duof is 200 mg to 400 mg taken orally every 12 hours. The dosage for children is not established as Duof is not recommended for individuals under 18 years of age due to potential side effects on bone and joint development.
How do I take Duof?
Duof can be taken with or without food, usually twice a day. It should be taken at the same times each day, spaced 12 hours apart. Avoid taking it within 2 hours of antacids, sucralfate, or supplements containing calcium, magnesium, aluminum, iron, or zinc to ensure proper absorption.
For how long do I take Duof?
The typical duration of use for Duof varies depending on the type and severity of the infection. It is usually taken for 3 days to 6 weeks. Your doctor will determine the exact length of treatment based on your specific condition.
What is Duof used for?
Duof is indicated for treating infections such as pneumonia, skin infections, bladder infections, reproductive organ infections, and prostate infections. It may also be used for bronchitis, urinary tract infections, and certain sexually transmitted diseases when other treatments are not available.
How long does it take for Duof to start working?
You should begin to feel better during the first few days of treatment with Duof. If your symptoms do not improve or worsen, contact your doctor for further evaluation.
Is Duof effective?
Duof is a fluoroquinolone antibiotic effective against a wide range of gram-negative and gram-positive bacteria. It works by inhibiting bacterial enzymes necessary for DNA replication. Clinical studies have shown its effectiveness in treating infections like pneumonia, skin infections, and urinary tract infections.
How does one know if Duof is working?
The benefit of Duof is evaluated through clinical improvement in symptoms and laboratory tests to check the body's response. Regular follow-ups with your doctor and laboratory tests may be necessary to ensure the medication is working effectively.
How does Duof work?
Duof works by inhibiting bacterial enzymes, specifically DNA gyrase and topoisomerase IV, which are necessary for DNA replication, transcription, repair, and recombination. This action effectively stops bacterial growth and kills the bacteria causing the infection.
Who should avoid taking Duof?
Important warnings for Duof include the risk of tendinitis and tendon rupture, peripheral neuropathy, and central nervous system effects. It is contraindicated in patients with a history of hypersensitivity to quinolones, epilepsy, or tendon disorders. Patients should avoid excessive sunlight exposure and inform their doctor of any history of heart, kidney, or liver issues.
Can I take Duof with vitamins or supplements?
Duof can interact with supplements containing calcium, magnesium, aluminum, iron, or zinc, which can reduce its absorption. It is recommended to take Duof at least 2 hours before or after these supplements to avoid interactions.
Can I take Duof with other prescription drugs?
Duof can interact with antacids, sucralfate, and multivitamins containing iron or zinc, reducing its absorption. It may also interact with non-steroidal anti-inflammatory drugs, increasing the risk of CNS stimulation. Patients should inform their doctor of all medications they are taking to avoid potential interactions.
Can Duof be taken safely while pregnant?
Duof is not recommended during pregnancy due to potential harm to the fetus, as animal studies have shown damage to joint cartilage in immature animals. There is limited human data, so it should only be used if the potential benefit justifies the risk to the fetus.
Can Duof be taken safely while breastfeeding?
Duof passes into breast milk and may cause serious adverse reactions in nursing infants. It is recommended to either discontinue breastfeeding or the medication, considering the importance of the drug to the mother.
Is Duof safe for the elderly?
Elderly patients are at increased risk for severe tendon disorders, including tendon rupture, when taking Duof. This risk is higher for those on corticosteroids. Dosage adjustments may be necessary for elderly patients with impaired renal function. Elderly patients should be informed of these risks and advised to contact their healthcare provider if symptoms occur.
How should I store Duof?
Store Duof in its original container, tightly closed, at room temperature away from excess heat and moisture. Keep it out of reach of children. Do not store it in the bathroom. Dispose of unneeded medication through a take-back program.
Does Duof make people tired or drowsy?
Commonly reported constitutional side effects of Duof include excessive tiredness. If you experience severe or persistent tiredness, it is important to contact your doctor. They may adjust your dosage or suggest an alternative treatment.
Does Duof cause stomach upset?
Common gastrointestinal side effects of Duof include nausea (10%), diarrhea (4%), vomiting (4%), and abdominal pain. If these symptoms are severe or persistent, contact your doctor. They may adjust your treatment or suggest ways to manage the side effects.
Does Duof affect sleep?
Insomnia is a reported side effect of Duof, occurring in about 3% of patients. If you experience difficulty sleeping, consult your doctor. They may recommend adjusting your dosage or switching to a different medication.
Does Duof make it hard to think or concentrate?
Cognitive side effects of Duof, such as confusion and memory problems, are rare but serious. If you experience these symptoms, stop taking the medication and contact your doctor immediately. They may need to adjust your treatment plan.
Does Duof affect mood?
Mental health side effects of Duof can include anxiety, depression, and confusion. These effects are rare but serious. If you experience any changes in mood or behavior, stop taking the medication and contact your doctor immediately for advice.
Does Duof affect appetite?
Duof may cause a change in appetite, including loss of appetite. If you experience a significant change in your eating habits, consult your doctor. They may adjust your dosage or suggest dietary adjustments to manage the side effect.
Does Duof cause weight gain?
Weight loss is a less common side effect of Duof. If you notice significant weight changes, consult your doctor. They may evaluate your condition and adjust your treatment plan if necessary.
Does Duof cause headaches?
Headaches are a common side effect of Duof, occurring in about 9% of patients. If you experience persistent or severe headaches, contact your doctor. They may recommend an over-the-counter pain reliever or adjust your medication.
Does Duof limit driving?
Duof can cause dizziness and lightheadedness, which may impair your ability to drive or operate machinery. Until you know how Duof affects you, avoid driving or engaging in activities that require full alertness and coordination.
Is it safe to exercise while taking Duof?
Duof may limit the ability to exercise due to its potential to cause tendinitis or tendon rupture, especially in the Achilles tendon. If you experience pain, swelling, or inflammation in a tendon, stop exercising and consult your doctor immediately.
What are Duof possible harms and risks?
Common side effects of Duof include nausea (10%), headache (9%), insomnia (7%), dizziness (5%), and diarrhea (4%). Serious adverse effects can include tendon rupture, peripheral neuropathy, and central nervous system effects. If you experience any severe side effects, contact your doctor immediately.
Available in 3 variations
Duof 100mg Tablet
Duof 100mg Tablet
Ofloxacin (100mg)
strip of 10 tablets
Duof 200mg Tablet
Duof 200mg Tablet
Ofloxacin (200mg)
strip of 10 tablets
Duof 400mg Tablet
Duof 400mg Tablet
Ofloxacin (400mg)
strip of 10 tablets
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