Dotidep 75mg Tablet

Dotidep 75mg Tablet belongs to the class of medications known as tricyclic antidepressants used primarily in the treatment of depression. This medication operates by elevating the levels of noradrenaline and serotonin in the brain. By impeding their reuptake, it amplifies their effects within the brain's synaptic cleft. 

Dosulepin's multifaceted mechanism also involves interaction with specific receptors, such as α2adrenoceptors and serotonin receptors, contributing to its antidepressant effects. Additionally, it affects histamine receptors, inducing sedation, and can lead to dry mouth through its action on muscarinic acetylcholine receptors.

It functions by inhibiting the reuptake of noradrenaline and serotonin, crucial neurotransmitters associated with mood regulation. By doing so, it heightens their levels in the brain, fostering an improved mood and relieving symptoms of depression Its interaction with various receptors further augments its antidepressant effects through multiple neurochemical pathways.

Adherence to your doctor's instructions regarding it is vital. It can be taken with or without food, but maintaining a consistent daily schedule is advisable for optimal results.

Some common side effects associated with this include dryness in the mouth, difficulty in urination, constipation, dizziness, sedation, and loss of accommodation.

Tricyclic antidepressants can affect the heart's conduction system, potentially leading to arrhythmias Individuals with a history of heart problems, recent myocardial infarction, heart block, or arrhythmias should inform their healthcare provider. Regular monitoring of cardiac function may be necessary.

It might increase intraocular pressure, which could worsen symptoms in individuals with glaucoma. Regular eye checkups are advisable for those with glaucoma.

If a dose of this drug is missed, it should be taken as soon as remembered. However, if the next dose is approaching, it's advised to skip the missed dose and continue with the regular dosing schedule. Avoid taking double doses to compensate for the missed one and consult your doctor for guidance on managing missed doses effectively.