Introduction to Deflazacort

Deflazacort is a medication primarily used to treat Duchenne muscular dystrophy (DMD), a condition that causes muscle weakening, in children aged 5 and older. It helps manage symptoms and improve quality of life.

Composition of Deflazacort

Deflazacort is a corticosteroid that works by reducing inflammation and suppressing the immune system. It converts into an active form that binds to the glucocorticoid receptor in cells, leading to a decrease in inflammatory substances.

Uses of Deflazacort

• Treatment of Duchenne muscular dystrophy (DMD) in children aged 5 and older.
• Reduction of inflammation in various conditions.
• Suppression of the immune system to manage autoimmune diseases.

Side Effects of Deflazacort

Common Side Effects:

• Weight gain
• Increased appetite
• Round face (Cushingoid appearance)
• Upper respiratory infections (common cold)
• Frequent urination
• Nose and throat inflammation
• Excessive hair growth
• Irritability

Serious Side Effects:

• Allergic reactions
• Severe mood changes
• High blood pressure
• Osteoporosis (bone weakening)

Precautions of Deflazacort

Deflazacort should not be taken by individuals who are allergic to it or any of its ingredients. Use with caution during pregnancy and breastfeeding. Avoid stopping the medication suddenly to prevent steroid withdrawal syndrome, which can cause symptoms like loss of appetite, nausea, vomiting, tiredness, and headache.

How to Take Deflazacort

• Take once daily by mouth.
• The recommended dose is about 0.9 mg per kilogram of body weight.
• Can be taken with or without food.
• Avoid taking with grapefruit juice.

Conclusion of Deflazacort

Deflazacort is an effective treatment for managing symptoms of Duchenne muscular dystrophy in children. It is important to follow the prescribed dosage and take necessary precautions to minimize side effects and ensure the best outcomes.