defnalone

Introduction to Defnalone

Defnalone is a medication primarily used to treat a condition known as Duchenne muscular dystrophy (DMD) in children aged 5 and older. This condition leads to muscle weakening, and Defnalone helps manage its symptoms.

Composition of Defnalone

Defnalone contains the active ingredient Deflazacort, which is a type of corticosteroid. Corticosteroids are a class of drugs that reduce inflammation and suppress the immune system.

Uses of Defnalone

• Treatment of Duchenne muscular dystrophy (DMD) in children aged 5 and older.
• Reduces inflammation in the body.
• Suppresses the immune system to prevent it from attacking the body's own tissues.

Side Effects of Defnalone

Common Side Effects:

• Weight gain
• Increased appetite
• Round face (Cushingoid appearance)
• Upper respiratory infections (common cold)
• Frequent urination
• Nose and throat inflammation
• Excessive hair growth
• Irritability

Serious Side Effects:

• Allergic reactions such as rash, itching, or swelling
• Severe dizziness
• Trouble breathing

Precautions of Defnalone

Defnalone should not be taken by individuals who are allergic to it or any of its ingredients. It should be used with caution during pregnancy and breastfeeding. Stopping Defnalone suddenly can lead to steroid withdrawal syndrome, which includes symptoms like loss of appetite, nausea, vomiting, tiredness, and headache.

How to Take Defnalone

• Take Defnalone once daily by mouth.
• The recommended dose is about 0.9 mg for each kilogram of body weight.
• It can be taken with or without food.
• Avoid taking it with grapefruit juice.

Conclusion of Defnalone

Defnalone is an effective medication for managing Duchenne muscular dystrophy in children. It works by reducing inflammation and suppressing the immune system. However, it is important to be aware of its side effects and take necessary precautions while using it. Always consult with a healthcare provider for personalized advice and guidance.