defagem

Introduction to Defagem

Defagem is a medication primarily used to treat a condition known as Duchenne muscular dystrophy (DMD) in children aged 5 and older. This condition leads to muscle weakening, and Defagem helps manage its symptoms.

Composition of Defagem

The active ingredient in Defagem is Deflazacort. It is a type of corticosteroid that helps reduce inflammation and suppress the immune system.

Uses of Defagem

• Treatment of Duchenne muscular dystrophy (DMD) in children
• Reduction of inflammation in the body
• Suppression of the immune system to manage symptoms

Side Effects of Defagem

Common Side Effects:

• Weight gain
• Increased appetite
• Round face (Cushingoid appearance)
• Upper respiratory infections (common cold)
• Frequent urination
• Nose and throat inflammation
• Excessive hair growth
• Irritability

Serious Side Effects:

• Allergic reactions such as rash, itching, or swelling
• Severe dizziness
• Trouble breathing

Precautions of Defagem

Defagem should not be taken by individuals who are allergic to it or any of its ingredients. It should be used with caution during pregnancy and breastfeeding. Stopping Defagem suddenly can lead to steroid withdrawal syndrome, which includes symptoms like loss of appetite, nausea, vomiting, tiredness, and headache.

How to Take Defagem

• Take Defagem once daily by mouth.
• The recommended dose is about 0.9 mg for each kilogram of body weight.
• It can be taken with or without food.
• Avoid taking it with grapefruit juice.

Conclusion of Defagem

Defagem is an effective medication for managing Duchenne muscular dystrophy in children. It helps reduce inflammation and suppress the immune system, providing relief from symptoms. However, it is important to follow the prescribed dosage and take necessary precautions to avoid potential side effects.