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clofranil (CLOMIPRAMINE)

Introduction to Clofranil


Clofranil is a medication primarily used to treat certain mental health conditions. It belongs to a class of drugs known as tricyclic antidepressants and is commonly prescribe... See More

Available in 4 variations

Clofranil 50mg Tablet 10s

Clofranil 50mg Tablet 10s

Clomipramine (50mg)

strip of 10 tablets

Clofranil 10 Tablet

Clofranil 10 Tablet

Clomipramine (10mg)

strip of 10 tablets

Clofranil 75mg Tablet SR 10s

Clofranil 75mg Tablet SR 10s

Clomipramine (75mg)

strip of 10 tablet pr

Clofranil 25mg Tablet 10s

Clofranil 25mg Tablet 10s

Clomipramine (25mg)

strip of 10 tablet

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What is Clofranil?

Clofranil is a medication used to treat obsessive-compulsive disorder. It belongs to a group of medicines called tricyclic antidepressants. Clofranil is available in capsule form and is taken by mouth. It can cause side effects such as drowsiness, dizziness, and seizures. It is important to take Clofranil exactly as prescribed by your doctor.

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What is the usual dose of Clofranil?

Start with a low dose and slowly increase it over two weeks. Adults go up to a maximum of 250mg a day, while children and teens have a maximum based on their weight, but no more than 200mg a day. Once the right dose is found, take it all at once before bed.

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How do I take Clofranil?

Clofranil is typically taken once daily, usually in the evening or before bedtime, to minimize daytime drowsiness. It should be swallowed whole with water and can be taken with or without food. Follow your doctor's dosing instructions carefully and do not stop or adjust the dose without consulting your healthcare provider.

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For how long do I take Clofranil?

Clofranil is typically used as a long-term treatment for chronic conditions such as Obsessive-Compulsive Disorder (OCD). While its effectiveness beyond 10 weeks has not been systematically evaluated in controlled trials, patients have continued therapy for up to one year without losing benefits during clinical studies. For chronic conditions like OCD, the duration of treatment depends on the individual's response and the healthcare provider's assessment, often involving periodic evaluations to determine the need for ongoing therapy​

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What is Clofranil used for?

Clofranil is a medication used to treat Obsessive-Compulsive Disorder (OCD), a condition that causes unwanted thoughts and repetitive behaviors. It works by increasing the levels of certain chemicals in the brain, which helps to reduce these symptoms.

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How long does it take for Clofranil to start working?

Clofranil may take 2 to 4 weeks to start showing noticeable effects, such as improvements in mood or reduced anxiety. However, it can take up to 6 to 8 weeks to experience its full therapeutic benefits. Be patient and continue taking the medication as prescribed, and follow up with your doctor for any concerns or side effects.

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Is Clofranil effective?

Clofranil, a medication used to treat moderate to severe OCD (obsessive-compulsive disorder), has been found to be effective in both adults and children and adolescents. Patients taking this medication typically experience a significant reduction in their symptoms, with an average improvement of 35-42% among adults and 37% among children and adolescents.

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How does one know if Clofranil is working?

You can tell Clofranil is working if you notice improvements in symptoms like reduced anxiety, obsessive thoughts, or compulsive behaviors and improvements in mood. It can take 2 to 4 weeks to start feeling better, and up to 6 to 8 weeks for full effects. Regular follow-ups with your doctor can help assess progress and adjust treatment if needed.

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How does Clofranil work?

Clofranil is a tricyclic antidepressant that works by increasing the levels of certain neurotransmitters in the brain, particularly serotonin and norepinephrine. These chemicals play a key role in regulating mood, anxiety, and other emotional responses. By enhancing their activity, Clofranil helps improve symptoms of conditions like depression, obsessive-compulsive disorder (OCD), and anxiety. It may also have mild effects on other brain chemicals, contributing to its therapeutic effects.

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Who should avoid taking Clofranil?

Clofranil hydrochloride capsules should not be used by people who: * Are allergic to Clofranil or other similar medications * Are taking or have recently taken certain medications called MAOIs, which are used to treat psychiatric disorders * Are taking linezolid or intravenous methylene blue, as these medications can increase the risk of a serious condition called serotonin syndrome

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Can I take Clofranil with vitamins or supplements?

Clofranil can be taken with vitamins or supplements, but be cautious with St. John's Wort or supplements that affect serotonin levels. Always consult your doctor before adding any new supplements.

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Can I take Clofranil with other prescription drugs?

Clofranil is a medication that can interact with other drugs. Some drugs can increase the levels of Clofranil in the body, which can be harmful. These drugs include quinidine, cimetidine, and fluoxetine. Other drugs, such as those that affect the brain or nervous system, should also be used with caution. Clofranil can also interact with drugs that lower blood pressure. Liver and kidney problems may affect how the body handles Clofranil, but more research is needed.

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Can Clofranil be taken safely while pregnant?

Clofranil should only be used during pregnancy if the potential benefits outweigh the potential risks to the baby. Studies in animals have not shown any birth defects, but withdrawal symptoms such as jitteriness, tremors, and seizures have been reported in newborns whose mothers took Clofranil until delivery.

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Can Clofranil be taken safely while breastfeeding?

Clofranil hydrochloride, a medication, can pass into breast milk. It's important to weigh the benefits of the medication for the mother against the potential risks to the baby. If the medication is essential for the mother's health, she may need to stop breastfeeding. If the medication is not essential, she may be able to continue breastfeeding. However, she should talk to her doctor about the risks and benefits of each option.

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Is Clofranil safe for the elderly?

For older people, start treatment carefully with low doses. This is because they may have issues with their liver, kidneys, or heart, or they may be taking other medications. They can also be more prone to having low sodium levels in their blood.

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How should I store Clofranil?

Keep this medication at room temperature between 68° to 77°F (20° to 25°C). Store it in a safe place where children cannot reach it. Keep the container tightly closed to protect the medication from moisture.

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Does Clofranil make people tired or drowsy?

Yes, Clofranil commonly causes tiredness or drowsiness, especially when starting treatment.

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Does Clofranil cause stomach upset?

Yes, Clofranil may cause stomach upset, including nausea or constipation, in some people.

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Does Clofranil affect sleep?

Clofranil can affect sleep. It may cause drowsiness or, in some cases, insomnia.

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Does Clofranil make it hard to think or concentrate?

Yes, Clofranil can cause difficulty concentrating or mental fog, particularly at the start of treatment or with dose increases.

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Does Clofranil affect mood?

Clofranil is used to improve mood in conditions like depression and OCD, but it may initially cause mood changes, such as irritability or restlessness, as a side effect.

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Does Clofranil interfere with sexual function?

Yes, Clofranil often affects sexual function, potentially causing reduced libido, delayed orgasm, or erectile dysfunction.

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Does Clofranil affect appetitie

Clofranil can affect appetite, leading to increased appetite or, less commonly, a reduced appetite.

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Does Clofranil cause weight gain?

Clofranil, a medication for OCD, can cause weight changes. Many more people taking it gained weight than those taking a sugar pill (placebo). A significant number gained a lot of weight. Some people lost weight, but fewer than those who gained weight. If your weight changes while on this medicine, talk to your doctor.

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Does Clofranil cause headaches?

Clofranil can cause headaches. More adults taking it got headaches than those taking a sugar pill (placebo). However, more children and teens on the placebo got headaches than those taking Clofranil. If you get a headache while taking this medicine, tell your doctor.

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Does Clofranil limit driving?

This medicine can make it hard to think clearly and move well. Don't drive or do anything dangerous while taking it. If you have trouble driving, stop driving right away and call your doctor.

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Is it safe to drink alcohol while taking Clofranil?

No, alcohol can increase the sedative effects of Clofranil and raise the risk of side effects like drowsiness or confusion.

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Is it safe to drink coffee or tea while taking Clofranil?

Yes, moderate consumption of coffee or tea is generally safe. However, excessive caffeine may worsen anxiety, restlessness, or insomnia.

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Is it safe to exercise while taking Clofranil?

Yes, moderate consumption of coffee or tea is generally safe. However, excessive caffeine may worsen anxiety, restlessness, or insomnia.

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What are Clofranil possible harms and risks?

Clofranil may cause side effects like upset stomach, nausea, and constipation. It can also make you feel sleepy, dizzy, or nervous. Some people may have problems with sexual function, like a lowered sex drive or trouble getting an erection. Other possible side effects include fatigue, sweating, increased appetite, weight gain, and changes in vision. In rare cases, Clofranil can cause a drop in sodium levels in the blood, which can be serious, especially in older adults.