axinate

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Axinate 60 Injection contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases. Belonging to the artemisinin class of medications holds a place on the World Health Organization's List of Essential Medicines.

It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA). This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins. Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels.

While generally well-tolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported.

It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester. It is generally safe for use in children, with adjustments in dosing for those under 20 kg. Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin.

In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action. The timing and severity of the missed dose will be considered to determine the most suitable response.

Available in 3 variations

Axinate 120mg Injection

Artesunate (120mg)

vial of 1 Injection

MRP : ₹389

Axinate 60 Injection

Artesunate (60mg)

vial of 1 Powder for Injection

MRP : ₹180

Axinate 60mg Injection

Artesunate (60mg)

vial of 1 Injection

MRP : ₹199

Related Faqs

Is Malart banned in India?

In India the accessibility of certain medications is strictly controlled and monitored One such medicine requiring a doctors prescription is available exclusively through this regulated process This practice aims to ensure the safety and wellbeing of individuals by preventing the misuse or improper administration of potentially harmful drugs By implementing these restrictions the government and medical authorities aim to minimize the risks associated with selfmedication and encourage individuals to consult a healthcare professional for proper diagnosis and prescription This system plays a crucial role in safeguarding public health and upholding ethical standards in the pharmaceutical industry Therefore if one wishes to obtain this particular medicine in India it is essential to consult a qualified doctor who can assess the individuals condition and prescribe the appropriate treatment By following this established protocol individuals can receive the necessary medication while also prioritizing their health and wellbeing

Where does Arinatem come from?

Artemisinin a compound with potent antimalarial properties is sourced from the Artemisinin tree This tree also known as sweet wormwood or Qing Hao in traditional Chinese medicine has been used for centuries in the treatment of various ailments The extraction of artemisinin from the leaves of this tree revolutionized the field of malaria treatment offering a more effective and fasteracting solution compared to conventional drugs Artemisinins remarkable effectiveness against malaria is attributed to its unique chemical structure which allows it to target and eliminate the malaria parasites in the blood When ingested artemisinin reacts with iron from the parasites producing free radicals that damage the parasites cellular structures leading to their demise This mode of action sets artemisinin apart from other antimalarial drugs and has contributed to its widespread use in combating malaria particularly in regions where drug resistance has become a significant concern In addition to its antimalarial properties artemisinin has shown promising potential in treating various other diseases and conditions Recent studies have indicated its effectiveness against certain types of cancer including leukemia and breast cancer It has also demonstrated antiinflammatory immunosuppressive and antiviral activities Although further research is needed to harness its full therapeutic potential artemisinins versatility and unique mode of action make it a promising candidate for future drug development Overall the derivation of artemisinin from the Artemisinin tree has led to significant advancements in the treatment of malaria and holds promise for tackling other diseases Its natural origin and potent properties make it a valuable resource in the ongoing battle against global health challenges

Where does Axinate come from?

Derived from the Artemisinin tree this natural compound has been a significant breakthrough in the field of medicine The Artemisinin tree scientifically known as Artemisia annua originates from the Asteraceae family and has been cultivated for centuries for its therapeutic properties The compound obtained from this tree has proven to be highly effective in treating malaria a lifethreatening disease caused by parasitic infection Since its discovery the use of this compound has revolutionized malaria treatment particularly in regions where drugresistant strains of the parasite have emerged Artemisininbased combination therapies ACTs which incorporate this compound have become the mainstay of malaria treatment worldwide The compounds unique mechanism of action targets the parasite within the red blood cells effectively eliminating the infection Furthermore research has shown promising results regarding the potential uses of Artemisinin in treating other diseases Its antiinflammatory and anticancer properties have sparked interest among scientists and ongoing studies are exploring its efficacy in various conditions such as autoimmune disorders and certain types of cancer The sustainable cultivation of the Artemisinin tree has also gained attention due to its impact on the environment and local communities Efforts are being made to promote responsible farming practices and ensure the fair trade of this valuable resource In conclusion the discovery and utilization of Artemisinin derived from the Artemisinin tree have yielded remarkable advancements in malaria treatment and have the potential to revolutionize the management of other diseases Its natural origin coupled with its effectiveness and growing body of research makes it a valuable asset in modern medicine

Is Alpasunate banned in India?

No in India this particular medication can only be obtained with a valid prescription from a licensed doctor It is not available overthecounter and cannot be purchased without proper authorization from a healthcare professional This regulation is in place to ensure the safe and responsible use of the medication as it may carry potential risks and side effects that need to be carefully considered by a qualified medical practitioner Purchasing medications without a prescription can pose serious health hazards and is generally discouraged Thus it is important to consult with a doctor who can assess your specific medical condition review your medical history and provide the necessary guidance on whether this medication is suitable for you Remember your health and wellbeing are of utmost importance and it is always best to follow the advice and recommendations of healthcare professionals to ensure the safe and effective management of your medical needs

How does Artesar work?

The mechanism of action of this particular compound involves the production of free radicals which have the capacity to effectively target and eliminate the malarial parasite known as Plasmodium By generating these highly reactive molecules this substance is able to disrupt vital processes within the parasite ultimately leading to its demise The production of free radicals is a critical step in the chain of events that result in the destruction of the malarial parasite This compounds unique ability to generate these radicals distinguishes it as an effective weapon against the Plasmodium parasite offering a promising approach for combating malaria As the free radicals are unleashed they directly attack specific targets within the parasite such as key proteins or cell membranes interfering with essential biological processes Consequently the malarial parasite is unable to survive leading to its complete eradication This innovative mechanism of action places this compound at the forefront of antimalarial treatments showcasing its potential for contributing to the global efforts in controlling and ultimately eliminating malaria

Where does Aisunate come from?

Derived from the Artemisinin tree this substance is highly sought after for its medicinal properties The Artemisinin tree also known as Sweet Wormwood or Qing Hao in Chinese is a plant native to Asia and has been used for centuries in traditional medicine The active compound extracted from this tree known as Artemisinin has been proven to be effective in treating malaria a deadly disease caused by parasites transmitted through mosquito bites Artemisinin is renowned for its powerful antimalarial properties as it targets and destroys the malaria parasites in the bloodstream This natural compound works by generating free radicals within the parasites causing irreversible damage to their cell membranes and ultimately leading to their death With the rise of drugresistant strains of malaria Artemisinin has become a crucial weapon in the fight against this global health crisis In addition to its antimalarial effects Artemisinin has also shown promise in treating other diseases such as cancer and inflammatory conditions Research has suggested that this natural compound has anticancer properties inhibiting the growth of cancer cells and inducing their death Furthermore it has been found to possess antiinflammatory and immunomodulatory effects making it a potential therapeutic agent for various inflammatory conditions including rheumatoid arthritis and inflammatory bowel disease Overall the remarkable properties of Artemisinin make it a valuable and versatile compound in the field of medicine With ongoing research and development this natural substance holds promise for the treatment of not only malaria but also other diseases afflicting humanity