Is Alfacalcidol the same as calcitriol?
Nov 3, 2023
Is Alfacalcidol the same as calcitriol?
However, alfacalcidol is a prohormone of calcitriol. It has to be converted by 25-hydroxylase at the liver to generate 1,25-dihydroxyvitamin D3 to act on target cells. Many pharmacokinetics studies demonstrate that alfacalcidol has lower AUC compared to calcitriol if they are administered in the same dose.
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