Trozet 2.5mg Tablet (LETROZOLE)

What is Trozet tablet?

Trozet tablet is a nonsteroidal aromatase inhibitor that reduces estrogen synthesis by inhibiting the aromatase enzyme. It is primarily used to treat hormone receptor-positive breast cancer in postmenopausal women​

What is the usual dose of Trozet tablet?

For grown-ups, the usual dose of Trozet tablet is one small pill (2.5 mg) once a day. It doesn't matter if you take it with or without food.
 

How do I take Trozet tablet?

Take one 2.5mg Trozet tablet pill each day. It doesn't matter if you take it with or without food.

 

For how long do I take Trozet tablet?

The duration of Trozet tablet therapy varies depending on the indication:

• Adjuvant Treatment of Early Breast Cancer: Median treatment duration is 5 years.
• Extended Adjuvant Treatment: Median duration is also around 5 years.
• Advanced Breast Cancer: Continue treatment until tumor progression is observed​

What is Trozet tablet used for?

Trozet tablet is a medicine for women who have gone through menopause and have breast cancer. It's used when the cancer's growth is fueled by hormones or when it's unclear if hormones play a role. It can treat advanced breast cancer that has spread, and it can also be used after surgery for early-stage breast cancer to help prevent the cancer from returning. Sometimes, it's used for a longer time after another medicine called tamoxifen.

 

How long does it take for Trozet tablet to start working?

Trozet tablet significantly reduces estrogen levels within 2 to 3 days of starting treatment.

Is Trozet tablet effective?

Trozet tablet is a medication used to treat breast cancer in postmenopausal women. It works best in cancers that are fueled by hormones. It can be used after other treatments like tamoxifen, even for a long time (up to 5 years after tamoxifen), to help prevent the cancer from returning. It's also used to treat advanced or spread breast cancer in these women. Studies show it's effective for many years.

 

How does one know if Trozet tablet is working?

The effectiveness is monitored through regular medical evaluations, imaging studies, and assessments of disease-free survival​

How does Trozet tablet work?

Trozet tablet is a medicine that's quickly absorbed into the body. It breaks down slowly into harmless substances and is mostly removed through the kidneys in urine. Most of the drug is found in the urine. It takes about 2 days for half of the drug to leave your body, and it takes several weeks to reach a stable level in your blood. Two liver enzymes, CYP3A4 and CYP2A6, help break it down.

Who should avoid taking Trozet tablet?

Trozet tablet is a medicine that shouldn't be taken by pregnant women because it can harm the baby. Women who can get pregnant need to use birth control during and for three weeks after taking it. It can sometimes weaken bones, so doctors will need to check on that. It can also cause tiredness and dizziness, so be careful driving or using machines. Your cholesterol might go up, so that needs checking too. If you have serious liver problems, you might need a lower dose.

 

Can I take Trozet tablet with vitamins or supplements?

There is no specific information on interactions with vitamins or supplements. Consult a healthcare provider before combining.

Can I take Trozet tablet with other prescription drugs?

Taking Trozet tablet with tamoxifen lowers the amount of Trozet tablet in the bloodstream, but it doesn't seem to affect how well Trozet tablet works if you take it after tamoxifen. Other drugs like cimetidine and warfarin don't appear to interact significantly with Trozet tablet. There's not much information about how Trozet tablet interacts with other cancer drugs.

 

Can Trozet tablet be taken safely while pregnant?

Trozet tablet is contraindicated in pregnancy due to its potential to cause fetal harm. It has been associated with spontaneous abortions and congenital defects​

Can Trozet tablet be taken safely while breastfeeding?

Women who are breastfeeding shouldn't take the medication Trozet tablet because it could seriously harm their babies. There's no information on how it affects babies who are breastfed, so it's best to avoid any risk. Breastfeeding should also be stopped for at least three weeks after finishing the medication.

 

Is Trozet tablet safe for the elderly?

Older people with metastatic breast cancer taking common treatments didn't show more problems or less benefit than younger people in studies. While bone density might decrease, doctors should watch for that. Even in long-term treatment, older patients (many over 65, some over 75) did just as well as younger patients.

How should I store Trozet tablet?

Store Trozet tablet at room temperature, between 20°C to 25°C (68°F to 77°F

Does Trozet tablet make people tired or drowsy?

Yes, fatigue is a common side effect (16.8%). Avoid driving or operating machinery if affected​.

Does Trozet tablet cause stomach upset?

Yes, nausea occurs in 11.6% of patients. Persistent symptoms should be reported to a healthcare provider.

Does Trozet tablet affect sleep?

Insomnia is reported in 5.8% of cases.  This might make it hard to sleep well, even if it doesn't directly cause sleep problems like insomnia. Because of this, be careful driving or using machinery until you know how Trozet tablet affects you. If your sleep is disrupted, talk to your doctor.

 

Does Trozet tablet make it hard to think or concentrate?

Dizziness and light-headedness are reported in 3.4% of cases. Caution is advised with tasks requiring focus​.

Does Trozet tablet affect mood?

Depression is reported in 4.9% of patients. If mood changes are severe, seek medical advice.

Does Trozet tablet interfere with sexual function?

Trozet tablet can cause vaginal dryness and reduced libido, but specific data on frequency are limited​.

Does Trozet tablet affect appetite?

No significant effects on appetite are reported.

Does Trozet tablet cause weight gain?

Weight increase occurs in 12.9% of cases​. The amount of weight gain can vary greatly depending on the medicine and the dose. For example, in some studies, a small percentage of people gained weight on a low dose of one medicine, while a much larger percentage gained weight on a high dose of a different medicine. If you notice you're gaining weight while taking medicine, talk to your doctor.

 

Does Trozet tablet cause headaches?

Yes, headaches are reported in 4.3% of patients.

Does Trozet tablet limit driving?

Femara can sometimes make you feel tired or dizzy, and rarely, sleepy. It's important to be careful when driving or using machinery until you know how the medicine affects you. If you have trouble driving, stop and call your doctor.

Is it safe to drink alcohol while taking Trozet tablet?

No specific interaction is noted, but alcohol may exacerbate side effects like dizziness or fatigue.

Is it safe to drink coffee or tea while taking Trozet tablet?

No evidence suggests that caffeine interacts with Trozet tablet​.

Is it safe to exercise while taking Trozet tablet?

Exercise is generally safe but monitor for fatigue or bone-related side effects like fractures or pain​.

What are Trozet tablet possible harms and risks?

The most common side effects were hot flashes, nausea, joint pain, and shortness of breath. Serious side effects, like blood clots in the legs or lungs, heart problems, and strokes, also happened, but were less common with Trozet tablet than with another similar drug, megestrol acetate.