Tentide AF 25mg Tablet (TENOFOVIR ALAFENAMIDE)
Introduction to Tentide AF 25mg Tablet
The Tentide AF 25mg Tablet is a medication primarily used to treat chronic hepatitis B virus (HBV) infections. It is suitable for patients aged 6 years and older... See More
What is Tentide af tablet?
Tentide af tablet is an antiviral drug used primarily for chronic hepatitis B virus (HBV) infections. It belongs to nucleoside reverse transcriptase inhibitors (NRTIs) and works by reducing the amount of the virus in the blood. While it doesn’t cure HBV, it prevents complications like cirrhosis and liver cancer by stopping viral replication.
What is the usual dose of Tentide af tablet?
The usual dose for adults and children aged 6 years or older weighing at least 25 kg is 25 mg taken once daily with food. No dose adjustment is needed for mild-to-moderate renal impairment, but patients with severe kidney or liver problems may require additional monitoring or alternative therapies.
How do I take Tentide af tablet?
Take Tentide af tablet exactly as prescribed by your doctor, once daily with food. It’s important to maintain a consistent dosing schedule. Do not skip doses, as missed doses may allow the virus to replicate, potentially leading to resistance.
For how long do I take Tentide af tablet?
Treatment duration depends on your condition and your doctor’s recommendation. Chronic HBV treatment is often long-term, sometimes for years, until lab results indicate it’s safe to stop. Regular monitoring is essential to assess the continued need for therapy.
What disease or symptom is Tentide af tablet used for?
Tentide af tablet is primarily prescribed for chronic hepatitis B in patients aged 6 years and older with compensated liver disease. It helps lower viral loads, reduces liver inflammation, and minimizes the risk of disease progression to cirrhosis or liver cancer.
How long does it take for Tentide af tablet to start working?
The medicine begins to lower HBV levels in the blood soon after starting treatment. However, significant improvement in liver function and viral suppression may take weeks to months, depending on the individual’s response and baseline condition.
Is Tentide af tablet effective?
Yes, clinical trials show Tentide af tablet is effective in suppressing HBV DNA in over 90% of patients by week 48. It also has a favorable safety profile compared to older drugs like Tenofovir disoproxil fumarate (TDF), especially in terms of kidney and bone health.
How do I know if Tentide af tablet is working?
Your doctor will monitor HBV DNA levels and liver enzyme tests (e.g., ALT) through periodic blood tests. Improvements in these values and reduced symptoms of liver damage indicate that the medication is working effectively.
How does Tentide af tablet work?
Tentide af tablet is a prodrug converted inside liver cells to its active form, tenofovir diphosphate. This compound blocks HBV reverse transcriptase, an enzyme required for viral replication, effectively halting the virus’s ability to reproduce.
Who should avoid taking Tentide af tablet?
Patients with severe liver impairment (Child-Pugh B or C), untreated HIV, or allergies to Tentide af tablet should avoid this medication. It should also not be used with certain drugs like rifampin or St. John’s Wort due to potential drug interactions.
Can I take Tentide af tablet with other prescription drugs?
Certain drugs, such as anticonvulsants (e.g., carbamazepine) and NSAIDs, may interfere with this medication, increasing the risk of kidney damage or reducing its effectiveness. Inform your doctor about all medications you are taking.
Can Tentide af tablet be taken safely while pregnant?
Studies show no significant risk of birth defects with Tentide af tablet use during pregnancy. However, your doctor will evaluate the benefits and risks, as HBV suppression during pregnancy can help prevent transmission to the baby.
Can Tentide af tablet be taken safely while breastfeeding?
Trace amounts of the drug can pass into breast milk, but no adverse effects have been reported in nursing infants. Discuss with your doctor whether to continue breastfeeding while on this medication, especially if you are HBV-positive.
Is Tentide af tablet safe for the elderly?
Yes, Tentide af tablet is generally safe for elderly patients, but they may require closer monitoring due to the potential for age-related kidney or liver function changes. Doctors may recommend routine blood tests for safety.
How should I store Tentide af tablet?
Store this medicine at room temperature (20–25°C) in a dry place, away from heat and moisture. Keep it in its original container and out of reach of children. Dispose of expired medication safely through a take-back program.
Does Tentide af tablet make people tired or drowsy?
Fatigue is a reported side effect in 6% of users. If you feel unusually tired, avoid driving or operating machinery. Let your doctor know if the fatigue becomes severe or persistent.
Does Tentide af tablet cause stomach upset?
Yes, nausea (6%), abdominal pain (9%), and diarrhea (5%) are common. To reduce these symptoms, take the medication with food. If symptoms worsen, consult your doctor for advice.
Does Tentide af tablet affect sleep?
Most people tolerate this medicine well and difficulty sleeping is not commonly reported. However, everybody can respond differently to medicines. Always track any changes you notice and let your doctor know when new symptoms are concerning - this will help make sure this medicine is right for you.
Does Tentide af tablet make it hard to think or concentrate?
Most people tolerate this medicine well and difficulty thinking or concentrating is not commonly reported. However, everybody can respond differently to medicines. Always track any changes you notice and let your doctor know when new symptoms are concerning - this will help make sure this medicine is right for you.
Does Tentide af tablet affect mood?
Most people tolerate this medicine well and changes in mood or increased anxiety is not commonly reported. However, everybody can respond differently to medicines. Always track any changes you notice and let your doctor know when new symptoms are concerning - this will help make sure this medicine is right for you.
Does Tentide af tablet interfere with sexual function?
Most people tolerate this medicine well and changes in appetite are not commonly reported. However, everybody can respond differently to medicines. Always track any changes you notice and let your doctor know when new symptoms are concerning - this will help make sure this medicine is right for you.
Does Tentide af tablet affect appetite?
Most people tolerate this medicine well and changes in appetite are not commonly reported. However, everybody can respond differently to medicines. Always track any changes you notice and let your doctor know when new symptoms are concerning - this will help make sure this medicine is right for you
Does Tentide af tablet cause weight gain?
Most people tolerate this medicine well and weight loss or weight gain is not commonly reported. However, everybody can respond differently to medicines. Always track any changes you notice and let your doctor know when new symptoms are concerning - this will help make sure this medicine is right for you.
Does Tentide af tablet cause headaches?
Headaches are the most common side effect, reported by 12% of patients. Over-the-counter pain relievers may help, but consult your doctor if the headaches are severe or persistent.
Does Tentide af tablet limit driving?
Most people tolerate this medicine well and it should not limit your ability to drive. However, everybody can respond differently to medicines. Always track any changes you notice and let your doctor know when new symptoms are concerning - this will help make sure this medicine is right for you.
Is it safe to drink alcohol while taking Tentide af tablet?
Moderate alcohol consumption is generally safe but may increase liver strain, particularly in patients with hepatitis B. It’s best to limit or avoid alcohol to protect liver health.
Is it safe to drink coffee or tea while taking Tentide af tablet?
Yes, drinking coffee or tea is safe and does not affect the medication’s effectiveness. However, excessive caffeine consumption may worsen side effects like insomnia or dizziness.
Is it safe to exercise while taking Tentide af tablet?
Exercise is generally safe and encouraged to maintain overall health. However, if you feel fatigued or experience side effects like dizziness, consider reducing the intensity of your activity and consult your doctor.
What are Tentide af tablet possible harms and risks?
Common side effects include headache (12%), abdominal pain (9%), fatigue (6%), and nausea (6%). Serious risks include kidney damage, lactic acidosis, and worsening liver function. Regular blood tests are needed to monitor for these complications.
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