Silostride Capsule (SILODOSIN)
Introduction to Silostride Capsule
The Silostride Capsule is a medication primarily used to treat symptoms of benign prostatic hyperplasia (BPH). This condition involves the enlargement of the prostate... See More
What is Silostride capsule?
Silostride capsule is used to treat symptoms of an enlarged prostate, known as benign prostatic hyperplasia (BPH), in men. It works by relaxing the muscles in the bladder and prostate, which helps improve urine flow and reduce BPH symptoms.
What is the usual dose of Silostride capsule?
The usual daily dose for adults is 8 mg taken orally once a day with a meal. Silostride capsule is not indicated for use in children, so there is no recommended dose for pediatric patients.
How do I take Silostride capsule?
Silostride capsule should be taken once daily with a meal to ensure proper absorption and reduce the risk of side effects. Patients should discuss with their doctor about consuming grapefruit or grapefruit juice while on this medication.
For how long do I take Silostride capsule?
Silostride capsule is used to manage symptoms of benign prostatic hyperplasia (BPH) and is typically taken long-term. It does not cure BPH but helps control symptoms, so it should be continued as prescribed by a healthcare provider.
What is Silostride capsule used for?
Silostride capsule is indicated for the treatment of symptoms associated with benign prostatic hyperplasia (BPH) in men, such as difficulty urinating, weak stream, and frequent urination.
How long does it take for Silostride capsule to start working?
Silostride capsule can start improving symptoms of benign prostatic hyperplasia (BPH) from the first scheduled observation, with significant symptom relief observed within the first few days of treatment.
Is Silostride capsule effective?
Clinical studies have shown that Silostride capsule significantly improves symptoms of benign prostatic hyperplasia (BPH), such as urinary flow rate and International Prostate Symptom Score (IPSS). Patients reported symptom relief starting from the first scheduled observation and continuing through 12 weeks of treatment.
How does one know if Silostride capsule is working?
The benefit of Silostride capsule is evaluated by monitoring the improvement in symptoms of benign prostatic hyperplasia (BPH), such as urinary flow rate and the International Prostate Symptom Score (IPSS). Regular follow-ups with a healthcare provider help assess its effectiveness.
How does Silostride capsule work?
Silostride capsule is a selective antagonist of post-synaptic alpha-1 adrenoreceptors, which are located in the prostate and bladder. By blocking these receptors, Silostride capsule relaxes smooth muscle in these tissues, improving urine flow and reducing BPH symptoms.
Who should avoid taking Silostride capsule?
Silostride capsule is contraindicated in patients with severe renal or hepatic impairment and those taking strong CYP3A4 inhibitors. It may cause orthostatic hypotension, so caution is advised when standing up quickly. Patients should inform their doctor if they have a history of low blood pressure or are undergoing eye surgery.
Can I take Silostride capsule with other prescription drugs?
Silostride capsule should not be used with strong CYP3A4 inhibitors like ketoconazole, as they can increase Silostride capsule levels in the blood. Caution is advised when used with other alpha-blockers or PDE5 inhibitors, as they can cause symptomatic hypotension.
Can Silostride capsule be taken safely while pregnant?
Silostride capsule is not indicated for use in women, especially during pregnancy. There is no strong evidence from human studies on fetal harm, but it is advised that pregnant women avoid this medication.
Can Silostride capsule be taken safely while breastfeeding?
Silostride capsule is not indicated for use in women, including those who are breastfeeding. Therefore, it should not be used by breastfeeding mothers.
Is Silostride capsule safe for the elderly?
Elderly patients may experience orthostatic hypotension more frequently. It's important for them to rise slowly from sitting or lying positions to prevent dizziness or fainting. Regular monitoring by a healthcare provider is recommended to ensure safe use.
How should I store Silostride capsule?
Store Silostride capsule at room temperature, between 20°C to 25°C (68°F to 77°F), away from excess heat and moisture. Keep it in its original container, tightly closed, and out of reach of children. Do not store it in the bathroom.
Does Silostride capsule make people tired or drowsy?
Silostride capsule may cause dizziness, which can be considered a constitutional side effect. This is more common when starting the medication. If you experience dizziness, avoid driving or operating machinery until you know how the medication affects you. If dizziness persists or worsens, contact your doctor.
Does Silostride capsule cause stomach upset?
Diarrhea is a commonly reported gastrointestinal side effect of Silostride capsule, occurring in about 2.6% of patients. If you experience diarrhea, stay hydrated and consult your doctor if it persists or becomes severe.
Does Silostride capsule affect sleep?
Insomnia has been reported in 1% to 2% of patients taking Silostride capsule. If you experience insomnia, discuss it with your doctor. They may adjust your dosage or suggest ways to manage this side effect.
Does Silostride capsule interfere with sexual function?
A common sexual side effect of Silostride capsule is retrograde ejaculation, occurring in about 28.1% of patients. This condition is reversible upon discontinuation of the medication. If you experience this or other sexual side effects, discuss them with your doctor.
Does Silostride capsule cause headaches?
Headaches are reported in about 2.4% of patients taking Silostride capsule. If you experience headaches, you can take over-the-counter pain relief, but consult your doctor if the headaches persist or worsen.
Does Silostride capsule limit driving?
Silostride capsule can cause dizziness or lightheadedness, especially when starting the medication. It is advised not to drive or operate heavy machinery until you know how Silostride capsule affects you. If you experience these symptoms, avoid driving and consult your doctor.
Is it safe to exercise while taking Silostride capsule?
Silostride capsule may cause dizziness or lightheadedness, especially when you first start taking it. This could potentially affect your ability to exercise safely. If you experience these symptoms, it is advisable to avoid strenuous activities until you know how the medication affects you.
What are Silostride capsule possible harms and risks?
Common side effects of Silostride capsule include retrograde ejaculation (28.1%), dizziness (3.2%), diarrhea (2.6%), and headache (2.4%). A serious adverse effect is a painful erection lasting several hours, which requires immediate medical attention.
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