paliris (PALIPERIDONE)
Introduction to Paliris
Paliris is a medication primarily used to treat mental health conditions such as schizophrenia and schizoaffective disorder. It helps manage symptoms like hallucinations, delusi... See More

What is Paliris?
Paliris is an antipsychotic medication used to treat schizophrenia and schizoaffective disorder. It helps restore the balance of certain neurotransmitters in the brain, improving mood, thinking, and behavior. It is available in extended-release tablet form and as an injectable. This medication reduces symptoms like hallucinations, delusions, and mood swings, helping patients lead a more stable life.

What is the usual dose of Paliris?
For schizophrenia, adults typically take 3 to 12 mg of Paliris daily, starting with 6 mg once a day. For schizoaffective disorder, doses range from 6 to 12 mg daily. Dosage is adjusted based on response and tolerance. The extended-release tablets should be swallowed whole, not chewed or crushed. Injectable doses vary depending on the formulation.

How do I take Paliris?
Paliris extended-release tablets should be taken once daily, in the morning, with or without food. They must be swallowed whole with water and should not be split or chewed. The injectable form is given by a healthcare professional. Avoid alcohol while taking this medication, as it can increase drowsiness and dizziness.

For how long do I take Paliris?
Treatment duration varies based on the condition. Schizophrenia and schizoaffective disorder often require long-term treatment to prevent relapse. Your doctor will determine the appropriate length of therapy. Do not stop taking Paliris suddenly, as it may cause withdrawal symptoms or worsen your condition.

What is Paliris used for?
Paliris is primarily used to treat schizophrenia and schizoaffective disorder. It helps manage symptoms such as hallucinations, delusions, mood instability, and disorganized thinking. By stabilizing dopamine and serotonin levels in the brain, it improves mental function and overall quality of life for people with these conditions.

How long does it take for Paliris to start working?
Paliris may start working within a few days, but full effects can take several weeks. Some symptoms like agitation or hallucinations may improve within 1 to 2 weeks, while others, such as disorganized thinking, may take longer. It is important to continue taking the medication as prescribed, even if symptoms improve.

Is Paliris effective?
Yes, studies show Paliris is effective in reducing schizophrenia and schizoaffective disorder symptoms. It helps prevent relapses and improves patients’ ability to function in daily life. The extended-release and injectable formulations provide consistent symptom control with fewer fluctuations in blood levels compared to older antipsychotic drugs.

How does one know if Paliris is working?
Improvement in symptoms such as reduced hallucinations, clearer thinking, and better emotional stability are signs that Paliris is working. It may take several weeks for full benefits. Regular follow-ups with a doctor will help monitor progress and adjust dosage if needed.

How does Paliris work?
Paliris blocks dopamine (D2) and serotonin (5-HT2A) receptors in the brain, reducing psychotic symptoms and mood instability. By balancing these neurotransmitters, it helps regulate emotions, thoughts, and behaviors, making it effective for schizophrenia and schizoaffective disorder.

Who should avoid taking Paliris?
People with severe kidney disease, a history of severe allergic reactions to Paliris or risperidone, or those with neuroleptic malignant syndrome (NMS) should avoid this medication. It should be used with caution in people with heart disease, seizures, or a history of low white blood cell counts.

Can I take Paliris with vitamins or supplements?
Paliris can interact with some supplements, especially St. John’s Wort, which may reduce its effectiveness. Calcium and magnesium supplements should be taken separately, as they can affect absorption. Always inform your doctor about any supplements you are taking before starting Paliris.

Can I take Paliris with other prescription drugs?
Paliris may interact with antihypertensive drugs, sedatives, antidepressants, and other antipsychotics, increasing the risk of side effects like drowsiness or low blood pressure. Avoid combining it with dopamine agonists like levodopa, as it may reduce their effectiveness. Always consult your doctor before adding new medications.

Can Paliris be taken safely while pregnant?
Paliris should only be used during pregnancy if the benefits outweigh the risks. In the third trimester, it may cause withdrawal symptoms in newborns, such as breathing difficulties and muscle stiffness. Pregnant women should consult their doctor for a thorough risk-benefit analysis before taking Paliris.

Can Paliris be taken safely while breastfeeding?
Paliris passes into breast milk and may cause side effects in infants, such as drowsiness or feeding difficulties. Breastfeeding while taking this medication is generally not recommended unless advised by a doctor. If necessary, formula feeding may be a safer alternative.

Is Paliris safe for the elderly?
Elderly patients, especially those with dementia-related psychosis, have an increased risk of stroke and death when using antipsychotics like Paliris. It should be used with caution in older adults due to increased sensitivity to side effects such as dizziness and movement disorders.

How should I store Paliris?
Store Paliris at room temperature (20-25°C) in a dry place, away from moisture and direct sunlight. Keep it out of reach of children. If using the injectable form, follow storage instructions provided by your healthcare provider. Do not use expired medication.

Does Paliris make people tired or drowsy?
Yes, drowsiness is a common side effect of Paliris, occurring in more than 10% of patients. Some people may feel fatigued or less alert, especially during the first few weeks. If drowsiness becomes severe, avoid activities that require concentration, like driving. Consult your doctor if it significantly affects your daily routine.

Does Paliris cause stomach upset?
Some people may experience nausea, constipation, or stomach discomfort while taking Paliris. These effects are usually mild and improve over time. Drinking plenty of fluids and eating fiber-rich foods can help. If symptoms persist or worsen, consult your doctor for possible dose adjustments or supportive treatments.

Does Paliris affect sleep?
Yes, Paliris can cause sleep disturbances, including insomnia or excessive sleepiness. Some patients find it harder to fall asleep, while others feel overly drowsy. If sleep problems persist, your doctor may adjust the dose or suggest taking the medication at a different time of day.

Does Paliris make it hard to think or concentrate?
Some people may experience difficulty concentrating, confusion, or memory problems while taking Paliris. These side effects are more common when starting the medication or after a dose increase. If cognitive issues interfere with daily life, discuss them with your doctor for possible dose adjustments.

Does Paliris affect mood?
While Paliris is used to stabilize mood, it may also cause mood swings, irritability, or emotional numbness in some patients. Rarely, it can lead to depression or suicidal thoughts. If you experience significant mood changes, inform your doctor immediately for proper management.

Does Paliris interfere with sexual function?
Yes, Paliris can affect sexual function by reducing libido, causing erectile dysfunction, or leading to delayed ejaculation. In women, it may cause changes in menstrual cycles due to increased prolactin levels. If these issues become bothersome, speak to your doctor about alternative treatments or management strategies.

Does Paliris affect appetite?
Paliris may increase appetite, leading to weight gain in some patients. Cravings for carbohydrates and increased hunger are common. If this leads to unhealthy weight changes, a balanced diet and regular exercise can help manage appetite.

Does Paliris cause weight gain?
Yes, weight gain is a frequently reported side effect of Paliris. Some patients may experience an increase in body fat due to higher appetite and metabolic changes. Regular physical activity and mindful eating habits can help prevent excessive weight gain while on this medication.

Does Paliris cause headaches?
Headaches are a common side effect, affecting some people, especially when starting Paliris. Staying hydrated and managing stress may help. If headaches become severe or persistent, talk to your doctor about potential adjustments or pain relief options.

Does Paliris limit driving?
Paliris can cause drowsiness, dizziness, and blurred vision, which may impair driving ability. If you feel overly sedated or unable to focus, avoid driving or operating machinery. Wait until you know how the medication affects you before engaging in activities requiring full alertness.

Is it safe to drink alcohol while taking Paliris?
Drinking alcohol while taking Paliris is not recommended. Alcohol can increase drowsiness, dizziness, and the risk of dangerous side effects like confusion or impaired motor skills. If you do drink, limit intake and monitor for adverse effects. Always consult your doctor before combining alcohol with medication.

Is it safe to drink coffee or tea while taking Paliris?
Caffeinated drinks like coffee and tea are generally safe with Paliris, but excessive caffeine may increase restlessness, anxiety, or heart rate changes. If you experience jitteriness or trouble sleeping, consider reducing caffeine intake. Always monitor your body’s reaction and adjust accordingly.

Is it safe to exercise while taking Paliris?
Yes, regular exercise is encouraged while taking Paliris to help manage weight gain and improve overall well-being. However, be cautious with strenuous activities, as this medication can cause dizziness, dehydration, or overheating. Stay hydrated, take breaks as needed, and consult your doctor if you experience unusual fatigue or weakness.

What are Paliris possible harms and risks?
Common side effects include drowsiness, weight gain, dizziness, and constipation. More serious risks include high blood sugar, movement disorders (extrapyramidal symptoms), and increased prolactin levels, which may cause hormonal changes. Rarely, it can cause neuroleptic malignant syndrome (NMS), a life-threatening condition. Regular medical check-ups help manage these risks.
Available in 4 variations

Paliris 9mg Tablet 14s
Paliris 9mg Tablet 14s
Paliperidone (9mg)
strip of 14 tablets

Paliris 1.5mg Tablet 14s
Paliris 1.5mg Tablet 14s
Paliperidone (1.5mg)
strip of 14 tablets

Paliris 3mg Tablet ER 7s
Paliris 3mg Tablet ER 7s
Paliperidone (3mg)
strip of 7 tablet er

Paliris 6mg Tablet 7s
Paliris 6mg Tablet 7s
Paliperidone (6mg)
strip of 7 tablets