orlisis (ORLISTAT)

What is Orlisis?

Orlisis is a medication used for weight loss. It works by inhibiting the absorption of fats in the digestive system

What is the usual dose of Orlisis?

• The usual dose is 120 mg taken three times a day with each main meal that contains fat.
• It is typically taken with meals or within 1 hour after a meal.

How do I take Orlisis?

• Take Orlisis with or up to 1 hour after a meal.
• It should be swallowed with water.
• If you miss a dose, skip it and take your next dose at the regular time.

For how long do I take Orlisis?

• Orlisis is usually taken as part of a long-term weight management plan.
• It is typically used for several months or longer, depending on your doctor’s advice and progress.

What disease or symptom is Orlisis used for?

Orlisis is used to help people with overweight or obesity achieve weight loss, particularly when combined with a low-calorie diet and regular physical activity.

How long does it take for Orlisis to start working?

Orlisis starts working within a few hours of taking it, as it inhibits the digestion and absorption of dietary fat.

Is Orlisis effective?

Orlisis is a medicine that helps people lose weight and keep it off. Studies showed that people taking it lost 3% more weight over two years than those taking a sugar pill (placebo). Also, people on Orlisis regained less weight after they'd already lost some, compared to those on the placebo. Those on the placebo regained a lot more of their lost weight.

How do I know if Orlisis is working?

Orlisis helped people lose weight in studies that lasted up to four years. These studies showed that people taking Orlisis lost more weight than those taking a sugar pill (placebo). It also helped prevent people from gaining the weight back after they'd lost it. Plus, it improved some health problems often linked to being overweight.

How does Orlisis work?

Orlisis works by inhibiting lipase, an enzyme responsible for breaking down fats in the digestive tract. This prevents the body from absorbing approximately 30% of the fat consumed.

Who should avoid taking Orlisis?

• People with chronic malabsorption syndrome (e.g., Crohn’s disease or other intestinal conditions).
• People with gallbladder problems.
• People who are pregnant or breastfeeding.
• People with allergies to Orlisis or any of its ingredients.

Can I take Orlisis with other prescription drugs?

• Orlisis may interact with medications like blood thinners, antidiabetic drugs, and anticonvulsants.
• Always inform your healthcare provider about other medications you are taking to avoid interactions.

Can Orlisis be taken safely while pregnant?

Orlisis is not recommended during pregnancy as it may affect the absorption of nutrients important for the developing baby.

Can Orlisis be taken safely while breastfeeding?

Orlisis is not recommended while breastfeeding, as it is not known if it passes into breast milk and may affect the infant’s nutrition.

Is Orlisis safe for the elderly?

Orlisis can be safe for the elderly but should be used with caution, particularly in those with kidney problems or other health concerns.

How should I store Orlisis?

Keep Orlisis in a cool, dry place between 59°F and 86°F (15°C and 30°C). Make sure the container is closed tightly. Don't use it after the date on the label.

Does Orlisis make people tired or drowsy?

Orlisis does not typically cause tiredness or drowsiness.

Does Orlisis cause stomach upset?

Yes, gastrointestinal side effects such as abdominal pain, gas, oily stools, and diarrhea are common.

Does Orlisis affect sleep?

Orlisis does not have a direct effect on sleep patterns.

Does Orlisis make it hard to think or concentrate?

No, Orlisis does not affect cognitive functions.

Does Orlisis affect mood?

Orlisis does not generally affect mood, but weight loss or gastrointestinal side effects may indirectly impact your well-being.

Does Orlisis interfere with sexual function?

Orlisis does not directly interfere with sexual function.

Does Orlisis affect appetite?

Orlisis does not directly affect appetite but can lead to some weight loss, which may indirectly influence hunger or food choices.

Does Orlisis cause weight gain?

Orlisis is used for weight loss, so it is not expected to cause weight gain unless the medication is not being taken properly or the diet is not followed.

Does Orlisis cause headaches?

Headaches are not common but may occur in some individuals taking Orlisis.

Does Orlisis limit driving?

Orlisis does not directly affect the ability to drive, but dizziness or fatigue may be side effects for some people.

Is it safe to drink alcohol while taking Orlisis?

Drinking alcohol in moderation is generally safe while taking Orlisis, but excessive alcohol consumption can affect your weight loss progress.

Is it safe to drink coffee or tea while taking Orlisis?

Yes, coffee and tea are safe to consume while taking Orlisis, but caffeine should be consumed in moderation

Is it safe to exercise while taking Orlisis?

Yes, exercise is encouraged while taking Orlisis as part of a healthy weight loss program. Regular physical activity supports overall weight management and health.

What are Orlisis possible harms and risks?

Common side effects include:

• Gastrointestinal issues: oily stools, flatulence, diarrhea, abdominal cramping
• Vitamin deficiencies: especially fat-soluble vitamins (A, D, E, K)
• Liver injury (rare)
• Kidney stones (rare)