jardiance (EMPAGLIFLOZIN)

What is Jardiance?

Jardiance is primarily used to treat type 2 diabetes and to reduce the risk of cardiovascular events in adults with both diabetes and heart disease. It works by inhibiting the SGLT2 protein in the kidneys, which prevents glucose from being reabsorbed back into the blood and promotes its excretion in urine, thereby lowering blood sugar levels. Jardiance also helps reduce excess weight and improve heart health.

What is the usual dose of Jardiance?

For adults, the usual starting dose of Jardiance for diabetes is 10 mg once a day, which may be increased to 25 mg once a day if needed. For heart failure or chronic kidney disease, the typical dose is 10 mg once a day. For children aged 10 years and older with type 2 diabetes, the starting dose is also 10 mg once a day, which can be increased to 25 mg if tolerated. Always follow your doctor's instructions.

How do I take Jardiance?

Jardiance can be taken with or without food. There are no specific food restrictions while using this medication. However, it is recommended to take it in the morning to maintain a consistent daily routine. Always follow your healthcare provider's instructions regarding the proper dosage and timing of the medicine.

For how long do I take Jardiance?

Jardiance is typically used for long-term treatment, often for life, in managing conditions like type 2 diabetes, heart failure, or chronic kidney disease. Do not stop taking it without consulting your doctor, as your condition may worsen.

What disease or symptom is Jardiance used for?

Jardiance is indicated for the following conditions:

1. Type 2 diabetes mellitus - to help control blood sugar levels.
2. Cardiovascular risk reduction - in adults with type 2 diabetes and cardiovascular disease to reduce the risk of heart attack, stroke, and related complications.
3. Heart failure - to reduce the risk of hospitalization for heart failure in certain patients with heart disease.

How long does it take for Jardiance to start working?

Jardiance starts lowering blood sugar within days, with full effects taking a few weeks. Cardiovascular benefits may take longer and require continued use.

Is Jardiance effective?

Clinical studies have shown that Jardiance effectively lowers blood sugar levels in people with type 2 diabetes and reduces the risk of cardiovascular events such as heart attack, stroke, and cardiovascular death in diabetic patients. It has also been proven to reduce hospitalization rates for heart failure and improve overall heart function. Research indicates significant benefits in weight loss and blood pressure reduction, supporting its effectiveness in managing both diabetes and heart-related conditions.

How do I know if Jardiance is working?

The benefit of Jardiance is evaluated through monitoring blood sugar levels (hemoglobin A1c) to assess its effectiveness in controlling diabetes. For cardiovascular benefits, doctors track heart health indicators such as hospitalization rates for heart failure, heart attack, stroke, and cardiovascular death. Additionally, blood pressure and weight are monitored to assess the full range of benefits, including its impact on heart failure management. Regular follow-up and lab tests help evaluate how well the medicine is working.

How does Jardiance work?

Jardiance works by inhibiting the SGLT2 (sodium-glucose cotransporter 2) protein in the kidneys. This protein is responsible for reabsorbing glucose from urine back into the bloodstream. By blocking SGLT2, Jardiance prevents glucose reabsorption, causing excess glucose to be excreted in the urine, which helps lower blood sugar levels in people with type 2 diabetes. It also reduces blood pressure and promotes weight loss, benefiting patients with heart failure and cardiovascular disease.

Who should avoid taking Jardiance?

Jardiance warnings include risks of kidney problems, diabetic ketoacidosis (DKA), low blood pressure, and genital infections. It's contraindicated in patients with severe kidney impairment, end-stage renal disease, and those on dialysis. Monitor kidney function and hydration status while on the medication. Always consult a healthcare provider before use.

Can I take Jardiance with other prescription drugs?

Jardiance can interact with diuretics, increasing the risk of dehydration and low blood pressure. When combined with insulin or other diabetes medications, it may cause hypoglycemia. Blood pressure medications may also lower blood pressure further. Always consult your doctor before taking Jardiance with other medications.

Can Jardiance be taken safely while pregnant?

Jardiance is not recommended during pregnancy because there is not enough information about its effects on the baby. However, other diabetes medications, such as insulin and metformin, are safe to take during pregnancy.

Can Jardiance be taken safely while breastfeeding?

Jardiance is a medication that should not be used during breastfeeding. It is unknown how much of the medication passes into breast milk, but it is likely to be a small amount. There is a possibility that Jardiance could lower the baby's blood sugar level and affect the development and growth of their kidneys. However, this has not been proven. Due to the potential risks, it is recommended to avoid breastfeeding while taking Jardiance.

Is Jardiance safe for the elderly?

Elderly patients using Jardiance may have an increased risk of dehydration and urinary tract infections. It's important for them to stay hydrated and monitor for signs of infection. Regular check-ups with a doctor are recommended to ensure safe use.

How should I store Jardiance?

Keep Jardiance in its original bottle, closed tight, and away from kids. Store it in a room-temperature spot that's not too hot or humid, like a closet or pantry (but not in the bathroom).

Does Jardiance make people tired or drowsy?

Jardiance may cause side effects like feeling tired or weak. If these symptoms are severe or persistent, it's important to contact your doctor. They may adjust your treatment or suggest ways to manage these side effects.

Does Jardiance cause stomach upset?

Jardiance may cause gastrointestinal side effects like nausea and vomiting. If these symptoms are severe or persistent, contact your doctor. They may adjust your treatment or suggest ways to manage these side effects.

Does Jardiance affect sleep?

Most people tolerate this medicine well and difficulty sleeping is not commonly reported. If you do experience sleep disturbances, they are likely mild and temporary. It's important to monitor your symptoms and consult your healthcare provider if they become severe or persistent. Always report any new symptoms to your doctor.

Does Jardiance make it hard to think or concentrate?

Most people tolerate this medicine well and difficulty thinking or concentrating is not commonly reported. If you do experience mild cognitive symptoms, they are likely temporary. It's important to monitor your symptoms and consult your healthcare provider if they become severe or persistent. Always report any new symptoms to your doctor and consult them before stopping the medicine.

Does Jardiance affect mood?

Most people tolerate Jardiance well, and changes in mood or increased anxiety are not commonly reported. If you do experience mood changes, they are likely mild and transient. It's important to monitor your mental health and consult your healthcare provider if you notice severe or persistent changes in mood. Always report any new symptoms to your doctor.

Does Jardiance interfere with sexual function?

Most people tolerate this medicine well and sexual side effects are not commonly reported. If you experience changes in sexual function, they are likely mild and temporary. It's important to monitor your symptoms and consult your healthcare provider if they become severe or persistent. Always report any new symptoms to your doctor.

Does Jardiance affect appetite?

Most people tolerate this medicine well and changes in appetite are not commonly reported. If you notice a change in your appetite, it is likely mild and temporary. It's important to monitor your symptoms and consult your healthcare provider if they become severe or persistent. Always report any new symptoms to your doctor.

Does Jardiance cause weight gain?

Jardiance can cause weight loss as it helps the body excrete excess glucose through urine. If you experience significant or concerning weight changes, consult your doctor. They may adjust your treatment or provide guidance on managing weight.

Does Jardiance cause headaches?

Headaches are not commonly reported as a side effect of Jardiance. If you experience persistent or severe headaches, consult your doctor. They may adjust your treatment or suggest ways to manage the headaches.

Does Jardiance limit driving?

Jardiance may cause dizziness or lightheadedness, especially when standing up quickly. If you experience these symptoms, avoid driving or operating heavy machinery until you feel better. Consult your doctor if these symptoms persist.

Is it safe to drink alcohol while taking Jardiance?

Drinking alcohol can affect blood sugar levels, which may impact the effectiveness of Jardiance. Alcohol may cause a change in blood sugar, so it's important to discuss safe alcohol consumption with your doctor while taking this medication.

Is it safe to drink coffee or tea while taking Jardiance?

Most people tolerate Jardiance well, and it should not limit your ability to drink caffeinated beverages such as coffee or tea. There are no known interactions between Jardiance and caffeine that would interfere with the medicine's effectiveness or cause harm. However, it's always a good idea to consume caffeine in moderation and discuss any concerns with your healthcare provider.

Is it safe to exercise while taking Jardiance?

Jardiance does not specifically limit the ability to exercise. However, it can cause dehydration and low blood sugar, which might affect physical performance. It's important to stay hydrated and monitor blood sugar levels during exercise. Consult your doctor for personalized advice.

What are the most common side effects of Jardiance?

A side effect is an unwanted reaction to a medicine. Common side effects of Jardiance include increased urination, urinary tract infections, and yeast infections. These are generally mild and may go away as your body adjusts. It's important to note that new symptoms can occur when starting any medicine and may not be related to the drug. Always talk to your healthcare provider before stopping any medication.

Does Jardiance have adverse effects?

Adverse effects are unwanted or harmful effects caused by a medicine. Jardiance can cause side effects like urinary tract infections, increased urination, and yeast infections, which are common. Rare but serious effects include dehydration and ketoacidosis, which is a dangerous condition where the body produces too many acids. If you experience severe symptoms, seek medical help immediately. Always report new symptoms to your healthcare provider and consult them before stopping any medication.

Is Jardiance addictive?

Jardiance is not addictive and has no known potential for dependence. It does not cause physical or psychological addiction. You can take it as prescribed by your healthcare provider without worrying about addiction. Always follow your doctor's instructions and discuss any concerns you may have about your medication.

Does Jardiance have any safety warnings?

Jardiance has safety warnings, including the risk of dehydration, which can lead to dizziness or fainting. It may also increase the risk of urinary tract infections and ketoacidosis, a serious condition where the body produces too many acids. Watch for symptoms like excessive thirst, frequent urination, or abdominal pain. If you experience these, contact your doctor immediately. Always follow your healthcare provider's advice and report any unusual symptoms.

Is it safe to stop Jardiance?

Jardiance is used for managing chronic conditions like diabetes, which require long-term treatment. Stopping it suddenly can lead to uncontrolled blood sugar levels, increasing the risk of complications. There are no known withdrawal symptoms, but stopping without medical advice can be dangerous. Always consult your doctor before making any changes to your medication regimen.

How do I dispose of Jardiance?

If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.

What are Jardiance possible harms and risks?

The most common side effects of Jardiance include urinary tract infections (UTIs), increased urination, and thirst. More significant adverse effects can include kidney problems, low blood pressure (hypotension), diabetic ketoacidosis (DKA), and an increased risk of genital infections (especially in women). Rare but serious effects include acute kidney injury and dehydration. Always report any unusual symptoms to your healthcare provider.