defozone

Introduction to defozone

Deflazacort, marketed under the name defozone, is a medication primarily used to treat a condition known as Duchenne muscular dystrophy (DMD). This is a muscle weakening disease that affects children aged 5 and older. Defozone helps manage the symptoms and improve the quality of life for those affected by this condition.

Composition of defozone

Defozone contains the active ingredient Deflazacort. This compound works by reducing inflammation and suppressing the immune system. It transforms into an active form that binds to a part of cells called the glucocorticoid receptor, which helps in reducing the production of inflammatory substances.

Uses of defozone

• Treatment of Duchenne muscular dystrophy (DMD) in children aged 5 and older.
• Reduction of inflammation in various conditions.
• Suppression of the immune system to manage autoimmune diseases.

Side effects of defozone

Common side effects:

• Weight gain
• Increased appetite
• Round face (Cushingoid appearance)
• Upper respiratory infections (common cold)
• Frequent urination
• Nose and throat inflammation
• Excessive hair growth
• Irritability

Serious side effects:

• Allergic reactions such as rash, itching, or swelling
• Severe dizziness
• Trouble breathing

Precautions of defozone

Defozone should not be taken by individuals who are allergic to it or any of its ingredients. It should be used with caution during pregnancy and breastfeeding. Stopping defozone suddenly can lead to steroid withdrawal syndrome, which may cause symptoms like loss of appetite, nausea, vomiting, tiredness, and headache.

How to Take defozone

• Take defozone once daily by mouth.
• The recommended dose is about 0.9 mg for each kilogram of body weight.
• It can be taken with or without food.
• Avoid taking it with grapefruit juice.

Conclusion of defozone

Defozone is a valuable medication for managing Duchenne muscular dystrophy and other inflammatory conditions. While it offers significant benefits, it is important to be aware of its side effects and precautions. Always consult with a healthcare professional before starting or stopping defozone to ensure safe and effective use.