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cizine (CINNARIZINE)

Introduction to Cizine


Cizine is a widely recognized medication primarily used for the treatment of various conditions related to balance and motion sickness. It is known for its efficacy in alleviatin... See More
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What is Cizine?

Cizine is used to manage balance disorders and motion sickness symptoms, such as vertigo, nausea, and vomiting. It works by blocking calcium channels in the brain, reducing the activity of the vestibular system, which helps control balance and spatial orientation. This action helps alleviate symptoms associated with these conditions.

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What is the usual dose of Cizine?

For vestibular symptoms, adults, elderly, and children over 12 years should take two tablets three times a day. Children aged 5-12 years should take one tablet three times a day. For motion sickness, adults, elderly, and children over 12 years should take two tablets two hours before travel and one tablet every eight hours during the journey if necessary. Children aged 5-12 years should take one tablet two hours before travel and half a tablet every eight hours during the journey if necessary.

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How do I take Cizine?

Cizine should be taken orally, preferably after meals to reduce gastric irritation. The tablets can be sucked, chewed, or swallowed whole with water. There are no specific food restrictions, but it is advisable to avoid alcohol as it can enhance the sedative effects of the medication.

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What is Cizine used for?

Cizine is indicated for the maintenance therapy of balance disorders, including symptoms like vertigo, tinnitus, nystagmus, nausea, and vomiting, as seen in Meniere's Disease. It is also effective in controlling motion sickness. Consult your healthcare provider for personalized advice on its use for these conditions.

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How long does it take for Cizine to start working?

Cizine is absorbed relatively slowly, with peak serum concentrations occurring 2.5 to 4 hours after oral administration. The onset of action may vary depending on the individual and the condition being treated. Consult your healthcare provider for personalized advice on what to expect when starting Cizine.

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Is Cizine effective?

Cizine's effectiveness has been evaluated in clinical trials involving subjects with peripheral and cerebral circulatory disorders, vertigo, and motion sickness. These trials have shown that Cizine is effective in managing symptoms associated with these conditions, such as vertigo and nausea. However, individual responses may vary, and consulting a healthcare provider for personalized advice is recommended.

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How does one know if Cizine is working?

The benefit of Cizine is evaluated through clinical trials and post-marketing experiences. These studies assess its effectiveness in managing symptoms of balance disorders and motion sickness. Healthcare professionals monitor patients for symptom improvement and any adverse effects, adjusting treatment as necessary to ensure the best therapeutic outcome.

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How does Cizine work?

Cizine is a piperazine derivative that acts as an antihistamine. It works by blocking calcium channels, reducing the availability of calcium ions needed for muscle contractions. This action helps to alleviate symptoms of balance disorders by reducing the activity of the vestibular system, which controls balance and spatial orientation.

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Who should avoid taking Cizine?

Cizine should not be used by individuals with hypersensitivity to the drug or its excipients. It should be used cautiously in patients with Parkinson's disease, as it may aggravate symptoms. Avoid use in porphyria and be cautious in patients with hepatic or renal insufficiency. Cizine may cause drowsiness, so avoid driving or operating machinery if affected. Alcohol and CNS depressants can enhance its sedative effects.

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Can I take Cizine with other prescription drugs?

Cizine can interact with alcohol, CNS depressants, and tricyclic antidepressants, potentially enhancing their sedative effects. This can lead to increased drowsiness or sleepiness. It is important to inform your healthcare provider about all medications you are taking to avoid potential interactions and ensure safe use of Cizine.

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Can Cizine be taken safely while pregnant?

The safety of Cizine during pregnancy has not been established, and it is not advisable to use it during pregnancy. Animal studies have not shown teratogenic effects, but there is no strong evidence from human studies. Pregnant women should consult their healthcare provider for personalized advice and consider alternative treatments.

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Is Cizine safe for the elderly?

Elderly patients can use Cizine, but they should follow the same dosage as adults. However, due to the potential for increased sensitivity to side effects like drowsiness, it is important for elderly patients to be cautious, especially when engaging in activities that require alertness, such as driving. Consulting a healthcare provider for personalized advice is recommended.

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How should I store Cizine?

Cizine does not require any special storage conditions. It should be kept in its original packaging, away from moisture and heat, and out of reach of children. Always check the expiration date and consult a pharmacist if you have any concerns about the storage of your medication.

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Does Cizine make people tired or drowsy?

Cizine commonly causes drowsiness, with a reported frequency of 9.9%. If you experience drowsiness or sleepiness, it is advisable to avoid activities that require alertness, such as driving or operating machinery. If the drowsiness persists or becomes bothersome, consult your healthcare provider for advice. They may adjust your dosage or suggest an alternative treatment.

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Does Cizine cause stomach upset?

Cizine can cause nausea, with a reported frequency of 3.0%. Vomiting and upper abdominal pain are also reported but less common. If you experience these side effects, taking the medication after meals may help reduce gastric irritation. If symptoms persist or worsen, consult your healthcare provider for further advice.

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Does Cizine cause weight gain?

Cizine can cause weight gain, with a reported frequency of 1.5%. If you experience weight gain, it is important to maintain a balanced diet and engage in regular physical activity. If the weight gain becomes significant or concerning, consult your healthcare provider for further advice and possible adjustments to your treatment plan.

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Does Cizine cause headaches?

Headaches have been reported as a side effect of Cizine, although the frequency is not specified. If you experience headaches while taking this medication, consider using over-the-counter pain relief, such as paracetamol, and ensure you stay hydrated. If headaches persist or worsen, consult your healthcare provider for further advice.

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Does Cizine limit driving?

Cizine may cause drowsiness, especially at the start of treatment. If you experience drowsiness, it is advisable not to drive or operate machinery until you know how the medication affects you. Always prioritize safety and consult your healthcare provider if you have concerns about driving while taking Cizine.

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Is it safe to drink alcohol while taking Cizine?

Drinking alcohol while taking Cizine may enhance the sedative effects of the drug. This means that alcohol can increase drowsiness or sleepiness caused by Cizine, potentially affecting your ability to perform tasks that require alertness, such as driving or operating machinery. It is advisable to avoid alcohol consumption while taking this medication to prevent these enhanced effects.

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Is it safe to exercise while taking Cizine?

Cizine is a medication used to treat symptoms of motion sickness and vertigo, and to improve blood circulation in the brain. It may cause drowsiness, especially when you first start taking it. So, it is important to avoid driving or operating machinery until you know how this medication affects you.

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What are Cizine possible harms and risks?

The most frequently reported side effects of Cizine include somnolence (9.9%), nausea (3.0%), and increased weight (1.5%). Serious adverse effects are rare but can include extrapyramidal symptoms and cholestatic jaundice. If you experience any side effects, consult your healthcare provider for advice and possible adjustments to your treatment.

Available in 2 variations

Cizine Forte 75mg Tablet

Cizine Forte 75mg Tablet

Cizine Forte 75mg Tablet

Cinnarizine (75mg)

strip of 10 tablets

Cizine 25mg Tablet

Cizine 25mg Tablet

Cizine 25mg Tablet

Cinnarizine (25mg)

strip of 10 tablets