buldef

Introduction to Buldef

Buldef is a medication primarily used to treat certain muscle weakening conditions. It is particularly effective in managing symptoms associated with Duchenne muscular dystrophy (DMD) in children aged 5 and older. By reducing inflammation and suppressing the immune system, Buldef helps improve muscle strength and function.

Composition of Buldef

The active ingredient in Buldef is Deflazacort. This compound is a type of corticosteroid that works by transforming into an active form in the body, which then binds to the glucocorticoid receptor in cells. This binding initiates a series of actions that reduce inflammation and modulate the immune response.

Uses of Buldef

• Treatment of Duchenne muscular dystrophy (DMD) in children aged 5 and older
• Reduction of inflammation in various conditions
• Suppression of the immune system to prevent overactivity

Side Effects of Buldef

Common Side Effects:

• Weight gain
• Increased appetite
• Round face (Cushingoid appearance)
• Upper respiratory infections (common cold)
• Frequent urination
• Nose and throat inflammation
• Excessive hair growth
• Irritability

Serious Side Effects:

• Allergic reactions such as rash, itching, or swelling
• Severe mood changes or depression
• Vision problems
• Severe stomach pain

Precautions of Buldef

Before taking Buldef, it is important to inform your healthcare provider if you have any allergies to Deflazacort or any other ingredients in the medication. Use with caution during pregnancy and breastfeeding. Do not stop taking Buldef suddenly, as this can lead to steroid withdrawal syndrome, which includes symptoms like loss of appetite, nausea, vomiting, tiredness, and headache.

How to Take Buldef

• Take Buldef once daily by mouth.
• The recommended dose is approximately 0.9 mg per kilogram of body weight.
• It can be taken with or without food.
• Avoid taking it with grapefruit juice.

Conclusion of Buldef

Buldef is a valuable medication for managing Duchenne muscular dystrophy and other inflammatory conditions. By understanding its uses, side effects, and precautions, patients can effectively incorporate Buldef into their treatment plan under the guidance of a healthcare professional. Always follow the prescribed dosage and consult your doctor for any concerns or unusual symptoms.