buldef (DEFLAZACORT)
Introduction to Buldef
Buldef is a medication primarily used to treat certain muscle weakening conditions. It is particularly effective in managing symptoms associated with Duchenne muscular dystrophy... See More

What is Buldef?
Buldef is a corticosteroid used to treat Duchenne muscular dystrophy (DMD) by reducing inflammation and modifying the immune system. It helps improve muscle function and slows disease progression. The medication works by decreasing inflammation and altering immune responses.

What is the usual dose of Buldef?
For adults, the usual maintenance dose of Buldef is typically within the range of 3 to 18 mg per day, depending on the condition being treated. For children, the dose is often calculated based on body weight, typically ranging from 0.25 to 1.5 mg/kg/day. Always follow your doctor's specific dosage instructions.

How do I take Buldef?
Buldef can be taken with or without food, but should not be taken with grapefruit juice. If you have difficulty swallowing tablets, they can be crushed and mixed with applesauce. Always follow your doctor's instructions regarding dosage and administration.

For how long do I take Buldef?
The duration of Buldef use varies depending on the condition being treated and the patient's response to the medication. It can be used for short-term treatment of acute conditions or long-term management of chronic diseases. Always follow your doctor's guidance on the duration of use.

What disease or symptom is Buldef used for?
Buldef is primarily indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older. It helps improve muscle strength and function in individuals with this condition.

How long does it take for Buldef to start working?
Buldef typically begins to work within a few hours to a few days, depending on the condition being treated. However, noticeable improvements in symptoms may take longer. Always follow your doctor's guidance and report any concerns about effectiveness.

Is Buldef effective?
Buldef has been shown to be effective in treating Duchenne muscular dystrophy (DMD) by improving muscle strength and function. Clinical studies have demonstrated its benefits in managing symptoms and slowing disease progression in patients with DMD.

How do I know if Buldef is working?
The benefit of Buldef is evaluated through regular medical check-ups, where doctors assess symptom improvement and monitor for side effects. Blood pressure and lab tests may be conducted to ensure the medication is working effectively and safely.

How does Buldef work?
Buldef is a corticosteroid that reduces inflammation and alters the immune system's response. It works by decreasing the production of substances that cause inflammation and suppressing the immune system to prevent tissue damage.

Who should avoid taking Buldef?
Buldef should not be used by individuals with known hypersensitivity to the drug or its ingredients. It can cause serious side effects like adrenal insufficiency, Cushing's syndrome, and increased risk of infections. Patients should avoid live vaccines and inform their doctor of any existing health conditions before starting treatment.

Can I take Buldef with other prescription drugs?
Buldef interacts with CYP3A4 inhibitors and inducers, which can alter its effectiveness. It should not be used with grapefruit juice, and caution is advised when taken with drugs like clarithromycin or rifampin. Always inform your doctor of all medications you are taking.

Can Buldef be taken safely while pregnant?
Buldef should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. There is no strong evidence from human studies on fetal harm, but corticosteroids can cross the placenta and may affect fetal development. Consult your doctor for personalized advice.

Can Buldef be taken safely while breastfeeding?
Buldef can pass into breast milk and may affect a nursing infant. The benefits of breastfeeding should be weighed against the potential risks of the medication. Consult your doctor for personalized advice on using Buldef while breastfeeding.

Is Buldef safe for the elderly?
Elderly patients using Buldef should be monitored closely due to the increased risk of osteoporosis, hypertension, and other side effects. It's important to use the lowest effective dose and to have regular check-ups with a healthcare provider to manage any potential complications.

How should I store Buldef?
Store Buldef in its original container, tightly closed, at room temperature away from excess heat and moisture. Do not store it in the bathroom. Dispose of any unused suspension liquid after one month. Keep it out of reach of children.

Does Buldef make people tired or drowsy?
Buldef does not commonly cause drowsiness or fatigue. However, if you experience any unusual tiredness or sleepiness, it's important to discuss these symptoms with your doctor. They may adjust your dosage or suggest ways to manage these side effects.

Does Buldef cause stomach upset?
Common gastrointestinal side effects of Buldef include upset stomach and heartburn. If you experience severe or persistent abdominal pain, nausea, or vomiting, contact your doctor. They may adjust your dosage or recommend treatments to alleviate these symptoms.

Does Buldef affect sleep?
Buldef can cause difficulty falling asleep or staying asleep, which is a common side effect. If you experience insomnia, talk to your doctor. They may adjust your dosage or suggest lifestyle changes to help improve your sleep quality.

Does Buldef make it hard to think or concentrate?
Buldef may cause cognitive side effects such as confusion or difficulty concentrating. If you experience these symptoms, consult your doctor. They may adjust your dosage or suggest strategies to help manage these cognitive changes.

Does Buldef affect mood?
Buldef can cause mood changes, irritability, and anxiety. If you experience these mental health side effects, it's important to contact your doctor. They may adjust your dosage or provide additional support to help manage these symptoms.

Does Buldef interfere with sexual function?
Most people tolerate Buldef well, and sexual side effects are not commonly reported. If you experience issues like erectile dysfunction or loss of libido, they are likely mild and transient. For persistent or severe symptoms, consult your healthcare provider. Always report new symptoms and discuss concerns with your doctor.

Does Buldef affect appetite?
Buldef commonly causes an increased appetite. If you notice significant changes in your eating habits, discuss them with your doctor. They may provide dietary advice or adjust your treatment plan to help manage this side effect.

Does Buldef cause weight gain?
Buldef often causes weight gain, which is a common side effect. If you experience significant weight changes, talk to your doctor. They may provide dietary advice or adjust your treatment plan to help manage this side effect.

Does Buldef cause headaches?
Headaches are a common side effect of Buldef. If you experience frequent or severe headaches, consult your doctor. They may adjust your dosage or recommend treatments to help alleviate the pain.

Does Buldef limit driving?
Buldef may cause dizziness or mood changes, which could affect your ability to drive safely. If you experience these symptoms, avoid driving and consult your doctor for advice. They may adjust your dosage or suggest ways to manage these side effects.

Is it safe to drink alcohol while taking Buldef?
Most people tolerate Buldef well, and occasional alcoholic drinks should not affect the way this medicine works. There are no well-established interactions between Buldef and alcohol. However, alcohol can increase the risk of stomach irritation and other side effects. It's best to consume alcohol in moderation and consult your healthcare provider if you have any concerns.

Is it safe to drink coffee or tea while taking Buldef?
Most people tolerate Buldef well, and it should not limit your ability to drink caffeinated beverages like coffee or tea. There are no known interactions between Buldef and caffeine that would interfere with the medicine's effectiveness or cause harm. However, it's always a good idea to consume caffeine in moderation and consult your healthcare provider if you have any concerns.

Is it safe to exercise while taking Buldef?
Buldef does not inherently limit the ability to exercise. However, it may cause muscle weakness or joint pain, which could affect physical activity. If you experience these symptoms, consult your doctor for advice on managing them while maintaining an exercise routine.

What are the most common side effects of Buldef?
A side effect is an unwanted effect of a medicine. Common side effects of Buldef include weight gain, increased appetite, mood changes, high blood pressure, and trouble sleeping. These may occur when starting the medicine and might not be related to it. Always talk to your healthcare provider before stopping any medicine, as they can help manage side effects.

Does Buldef have adverse effects?
Adverse effects are unwanted or harmful effects caused by a medicine. Buldef can cause adverse effects like weight gain, increased appetite, mood changes, and high blood pressure. Serious but rare effects include vision problems and severe mood swings, which need immediate medical attention. Always report new symptoms to your healthcare provider and consult them before stopping the medicine.

Is Buldef addictive?
Buldef is not known to be addictive or habit-forming. It does not cause physical or psychological dependence. However, it's important to follow your doctor's instructions and not to stop taking it suddenly without medical advice. If you have concerns about your medication, discuss them with your healthcare provider.

Does Buldef have any safety warnings?
Buldef comes with safety warnings. It can weaken the immune system, increasing infection risk. Watch for signs like fever or sore throat. It may cause high blood pressure or blood sugar changes, so monitor these regularly. Long-term use can lead to bone thinning, so discuss calcium supplements with your doctor. Always report unusual symptoms to your healthcare provider.

Is it safe to stop Buldef?
Buldef is often used for long-term management of chronic conditions. Stopping it suddenly can lead to withdrawal symptoms or a flare-up of the condition being treated. There may be life-threatening risks if stopped abruptly, especially if taken for a long time. Always consult your doctor before stopping Buldef to ensure a safe and gradual reduction in dosage.

How do I dispose of Buldef?
If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.

What are Buldef possible harms and risks?
Common side effects of Buldef include increased appetite, weight gain, and mood changes. Serious adverse effects can include infections, adrenal insufficiency, and Cushing's syndrome. If you experience severe side effects, contact your doctor immediately.
Available in 2 variations

Buldef 6 Tablet
Buldef 6 Tablet
Deflazacort (6mg)
strip of 10 tablets

Buldef 6mg Syrup
Buldef 6mg Syrup
Deflazacort (6mg)
bottle of 30 ml Oral Suspension