Axicralf 1000mg Suspension (SUCRALFATE)

What is Axicralf suspension?

Axicralf suspension is primarily used to treat and prevent ulcers in the stomach and intestines. It works by forming a protective barrier over the ulcer, shielding it from stomach acid and promoting healing. This medication is often used for conditions like gastric ulcers, duodenal ulcers, and acid reflux, as it helps to protect and soothe the digestive tract.

How do I take Axicralf suspension?

Axicralf suspension should be taken on an empty stomach, at least 1 hour before meals or 2 hours after meals for maximum effectiveness. It is important to not chew or crush the tablets; they should be swallowed whole with water. You should avoid taking antacids within 30 minutes of taking Axicralf suspension, as they can reduce its effectiveness.

For how long do I take Axicralf suspension?

The duration of Axicralf suspension treatment depends on the condition being treated:

For ulcers (gastric or duodenal):

• Typically, treatment lasts for 4 to 8 weeks, depending on the severity of the ulcer and how well it heals.

For gastroesophageal reflux disease (GERD):

• Axicralf suspension may be used for a shorter period, often 4 to 6 weeks, to help heal esophageal irritation.

Always follow your doctor's instructions for the specific duration tailored to your condition.

What is Axicralf suspension used for?

Axicralf suspension is used to treat and prevent peptic ulcers, gastritis, and duodenitis by forming a protective barrier over the ulcer or damaged area. It is also used to treat esophagitis caused by acid reflux and to prevent stress ulcers in critically ill patients. It helps protect the stomach lining from damage caused by certain medications.

How long does it take for Axicralf suspension to start working?

Axicralf suspension typically begins to work within 1 to 2 hours after taking it. However, noticeable improvement in symptoms, such as pain relief from ulcers, may take a few days to a few weeks depending on the severity of the condition being treated. It's important to complete the prescribed course for full healing.

Is Axicralf suspension effective?

Evidence supporting Axicralf suspension’s effectiveness comes from studies showing its ability to promote ulcer healing and reduce symptoms in patients with peptic ulcers. Clinical trials have demonstrated that Axicralf suspension creates a protective coating over ulcers, helping to prevent further irritation from stomach acid and facilitating healing. It has also been shown to effectively reduce the recurrence of ulcers when used in the long term.

How does one know if Axicralf suspension is working?

The benefit of Axicralf suspension is evaluated by monitoring the healing of ulcers, reduction in symptoms (such as pain and discomfort), and the prevention of ulcer recurrence. This is typically assessed through clinical evaluation, endoscopic examination, and patient-reported outcomes. In some cases, tests like X-rays or endoscopy may be performed to confirm the healing process and ulcer closure.

How does Axicralf suspension work?

Axicralf suspension works by forming a protective barrier over the ulcers or damaged areas in the stomach and intestines. When it comes into contact with stomach acid, it binds to the ulcer surface, creating a gel-like coating that shields the ulcer from further damage and promotes healing. This barrier also protects the stomach lining from acids, bile, and other irritants.

Who should avoid taking Axicralf suspension?

Axicralf suspension should be used with caution in individuals with kidney problems, as it can cause aluminum buildup. It is contraindicated in patients with hypersensitivity to the drug or its components. Caution is also advised when using it alongside other medications, as it can interfere with their absorption. It should not be taken within 2 hours of antacids, as this may reduce its effectiveness.

Can I take Axicralf suspension with vitamins or supplements?

Axicralf suspension may interfere with the absorption of certain vitamins and minerals, particularly calcium, magnesium, and phosphorus. It can also affect the absorption of fat-soluble vitamins like A, D, E, and K. It's recommended to take Axicralf suspension at least 2 hours before or after vitamin and mineral supplements to avoid these interactions.

Can I take Axicralf suspension with other prescription drugs?

Axicralf suspension can interact with several medications. Antacids, H2 blockers, and phenytoin may reduce its effectiveness. It may also interfere with the absorption of warfarin, potentially increasing bleeding risk. To avoid interactions, Axicralf suspension should be taken separately from these drugs, typically 30 minutes apart. Always consult a healthcare provider before combining Axicralf suspension with other medications.

Can Axicralf suspension be taken safely while pregnant?

Axicralf suspension is generally considered safe during pregnancy, as studies show no significant risks to fetal development. It is classified as a Category B medication by the FDA, meaning animal studies have not shown harm, but there are limited human studies. Pregnant women should consult a doctor before using Axicralf suspension to ensure it is appropriate for their condition.

Can Axicralf suspension be taken safely while breastfeeding?

Axicralf suspension is considered safe for use during breastfeeding, as it is minimally absorbed into the bloodstream and is unlikely to affect the infant. However, it is always recommended that breastfeeding mothers consult their healthcare provider before using Axicralf suspension to ensure it is suitable for their specific situation.

Is Axicralf suspension safe for the elderly?

Yes, Axicralf suspension can be safe for the elderly, but it should be used with caution. Older adults may be more sensitive to certain side effects, such as constipation, which is a common issue with Axicralf suspension. Additionally, the elderly may have other health conditions or be taking medications that could interact with Axicralf suspension, so it’s important to follow the doctor's recommendations carefully.

Always consult with your healthcare provider before starting Axicralf suspension if you are elderly or have other medical conditions.

How should I store Axicralf suspension?

Axicralf suspension should be stored at room temperature, away from heat, moisture, and direct sunlight. It is important to keep it in its original packaging or container, tightly closed, to protect it from humidity. Keep it out of reach of children, and do not use it past its expiration date.

Does Axicralf suspension make people tired or drowsy?

No, Axicralf suspension does not usually cause tiredness or drowsiness.

Does Axicralf suspension cause stomach upset?

It can sometimes cause constipation or mild stomach discomfort, but it generally helps protect the stomach.

Does Axicralf suspension affect sleep?

It doesn’t typically affect sleep.

Does Axicralf suspension make it hard to think or concentrate?

No, Axicralf suspension doesn’t affect thinking or concentration.

Does Axicralf suspension affect mood?

Mood changes are not common with Axicralf suspension.

Does Axicralf suspension interfere with sexual function?

No, Axicralf suspension does not interfere with sexual function.

Does Axicralf suspension affect appetite?

Axicralf suspension doesn’t usually affect your appetite.

Does Axicralf suspension cause weight gain?

Axicralf suspension does not cause weight gain.

Does Axicralf suspension cause headaches?

Headaches are not common, but a few people may experience them.

Does Axicralf suspension limit driving?

Axicralf suspension doesn’t affect your ability to drive.

Is it safe to drink alcohol while taking Axicralf suspension?

It's best to avoid alcohol because it can irritate the stomach, which could interfere with the healing process.

Is it safe to drink coffee or tea while taking Axicralf suspension?

Yes, it’s safe to drink coffee or tea.

Is it safe to exercise while taking Axicralf suspension?

Yes, you can exercise while taking Axicralf suspension, as long as you feel fine.

What are Axicralf suspension possible harms and risks?

The most common side effects of Axicralf suspension include constipation, dry mouth, and stomach discomfort. Significant adverse effects, though rare, may include allergic reactions (such as rash or itching), gastrointestinal issues like nausea or vomiting, and dizziness. Severe side effects, including difficulty breathing or swelling, require immediate medical attention. Long-term use may lead to mineral imbalances.